Yintoni i-9-ME-BC?

I-9-Me-BC (9-Methyl-β-carboline) ekwabizwa ngokuba yi-9-MBC yindawo yenoveli ye-nootropic evela kwiqela le-β-carboline. I-Carbolines zivela kusapho lwe-carboline eyahlukileyo. Oku kuthetha ukuba ziveliswa zombini emzimbeni womntu kwaye ziveliswa kwiziqhamo ezithile, inyama ephekiweyo, umsi wecuba kunye nekofu.

Ii-β-Carbolines (BCs) zichongiwe njenge-neurotoxic, nangona kunjalo, kutshanje kufunyaniswe ukuba i-9-Me-Bc iluncedo. I-9-Me-BC yi-dopaminergic neuroprotector ekwaphucula ukusebenza kwengqondo.

I-9-Me-BC powder kunye ne-9-Me-BC capsule zongeza ifom yeyona nootropic ibalaseleyo. Kuba ngokungafaniyo nezinye ii-nootropics ezifumana isibonelelo emva kweeyure ezimbalwa, i-9-Me-BC ibonelela ngeziphumo ezihlala ixesha elide nezide. 

I-9-ME-BC powder- isebenza njani?

I-9-Me-BC ijikeleze kakuhle kakhulu i-nootropic ebonisa iindlela ezininzi zokwenza. Iindlela ezahlukeneyo ze-9-Me-BC zokwenza ukuba zisebenze kakhulu ekusebenzeni kwazo.

Apha ngezantsi kukho iindlela zokusebenza kwe-9-Me-BC;

  1. Iphakamisa inqanaba le-dopamine kwingqondo ngokuthintela ukonakala kwe-dopamine, ngokungafaniyo nezinye izinto ezinje nge-caffeine ecutha i-dopamine ngenxa yokukhutshwa gwenxa kunye nokusetyenziswa.
  2. I-9-Me-BC ivuselela umsebenzi we-dopamine, eyahlulahlula kunye nokukhusela ii-neurons, dendrites kunye nee-synapses kwingqondo. Kungenxa yoko le nto ikwazi ukuphucula ukufunda, inkumbulo kunye nomsebenzi wokuqonda
  3. Inefuthe kwi-tyrosine hydroxylase (TH) kunye nezinto ezikhutshelweyo ngelixa inxibelelana ne-tyrosine kinases. I-tyrosine kinases idlala indima ekuguqulweni kwe-L-tyrosine kwi-L-Dopa enoxanduva lokudityaniswa kwe-dopamine.
  4. I-9-Me-BC inqanda i-monoamine oxidase A kunye ne-B (MAOA kunye ne-MAOB) ke oko kuthintela ukuveliswa kweekhompawundi ze-neurotoxic ezinje nge-DOPAC kwi-dopamine metabolism. Ezi zinto zibangela ukufa kwee-dopaminergic neurons.
  5. I-9-Me-BC inyusa umxokelelwane wokuphefumla we-mitochondrial. Ukwenza oku ngokwandisa okanye ukukhusela i-NADH dehydrogenase, esetyenziswa kwinkqubo yokudlulisa i-electron yokwenza amandla.
  6. I-9-Me-BC inokonyusa izinto ze-neurotrophic ezinje ngeNerve grow factor (NGF), SHH (Sonic Hedgehog Signaling Molecule), Brain-derived neurotrophic factor (BDNF) eyandisa umsebenzi wokuqonda, ukugxila kunye nokukhuthaza.
  7. Ikhuthaza umsebenzi we-neuronal ngelixa ikwakhuthaza ukukhula kwee-neurons ezintsha. Oku kunyusa inkumbulo kunye nokufunda kunye nokusebenza kwengqondo ngokubanzi.
  8. Iipropati ezichasayo. I-9-me-BC iyenzeka ukulwa nokudumba okungapheliyo kwingqondo ngokunciphisa ii-cytokines ezivuthayo, ezaziwayo ukuba zibangela ukuqokelelwa kwe-microglial ethi yona iphazamise ukusebenza kwengqondo.

 

Izibonelelo ze-9-ME-BC-Njani yePowder ye-9-ME-BC (Nootropic) inokukunceda?

I-9-Me-BC zongeza Unoluhlu olubanzi lwezibonelelo zempilo. Izibonelelo ezahlukeneyo ze-9-Me-BC ziziphumo zeendlela ezininzi zezenzo ezibonisa.

Apha ngezantsi zizibonelelo ze-9-Me-BC;

 

i. Ngaba unokuphucula ukufunda, imemori kunye nokuqonda

I-9-Me-BC ivuselela imisebenzi ye-neurons kunye nokunyusa ukukhula kweeseli ezintsha ze-neuron. Oku kubaluleke kakhulu ekuphuculeni ukufunda, inkumbulo kunye nokusebenza kwengqondo ngokubanzi.

9-Me-BC nayo yonyusa iATP imveliso yamandla ngokuphucula ikhonkco lokuphefumla le-mitochondrial. Yiyo ke loo nto ukonyusa amandla okukhuthaza ukukhuthaza kunye nokulumka.

Kuphononongo lweempuku, isongezelelo se-9-Me-BC esinikwe iintsuku ezili-10 kwafunyanwa ukuphucula ukufunda. Isifundo sixele ukuba oku kubangelwe kukunyuka kwamanqanaba e-dopamine kunye nokukhuthaza ukukhula kwee-synapses kunye ne-dendrites. 

I-9-Me-BC

ii. Inceda ekulweni nokudumba

Ukudumba yindlela yendalo umzimba olwa ngayo nosulelo okanye ukwenzakala. Nangona kunjalo, ukudumba okungapheliyo kunokuba yingozi emzimbeni kwaye kunxulunyaniswa nezifo ezininzi ezinje ngeswekile kunye nomhlaza.

Yiyo loo nto kufuneka ukuba kuthintelwe olu dumbo ngaphambi kokuba lube yinto embi emzimbeni wakho. Ngethamsanqa, i-9-Me-BC powder inokunceda ukuthintela ukudumba okungapheliyo. Ilwa nokudumba ngokunciphisa ii-cytokines ezivuthayo.

 

iii. Unokuphucula i-libido

I-9-Me-BC ye-nootropic yecomputer ine-dopaminergic kakhulu. Iimpawu zeDopaminergic zaziwa ngokunyusa amanqanaba edopamine kwingqondo. Oku kukonyusa umsebenzi we-dopamine ohambelana kakhulu nokwanda kwe-libido.

 

iv. Inokuphucula ukusebenza kweembaleki

Isakhono se-9-Me-BC sonyusa imveliso yamandla kunye neemvakalelo kunye nenkuthazo yenza ukuba kube ngumgqatswa onokubakho ekuphuculeni ukusebenza kweembaleki.

Amava e-9-Me-BC: Uyisebenzisa kanjani i-9-MBC?

Isisombululo esinconywayo se-9-Me-BC sithatha i-capsule enye ye-9-Me-BC yonke imihla. I-capsule enye ye-9-Me-BC ilingana ne-15 mg ye-9-Me-BC powder.

Kuyacetyiswa ukuba uthathe i-capsule ye-9-Me-BC kusasa njengoko kusaziwa ngokwandisa ukuphaphama, imo yokhuthazo, nenkuthazo, oya kuyidinga ngexesha losuku.

 

Ngaba kukhuselekile kwaye kusemthethweni ukusebenzisa i-9-MBC? 9-me-bc umngcipheko?

I-9-MBC ithathwa njengekhuselekileyo ngokubanzi yokutya. Ukusuka kufundo lwesilwanyana, i-9-Me-BC nootropic elawulwa ngeentsuku ezili-10 yafunyanwa ikhuselekile ngokupheleleyo.

Nangona kunjalo, akukho datha iyafumaneka ngokubhekisele ekusebenziseni isongezelelo se-9-Me-BC ixesha elide kunye nokunqongophala kwezilingo ngokubhekisele kule 9-Me-BC nootropic.

Kuyacetyiswa ke ukuba ukhathalele xa uthatha le nootropic ngokuthatha ikhefu phakathi ukunqanda nayiphi na ingozi enokubakho ye-9-Me-BC. 

Isongezelelo se-9-Me-BC sisemthethweni kwilizwe ngalinye kwihlabathi liphela. Ihlelwe kwaye ithengiswa njengesongezelelo sokutya kungoko ilawulwa ngendlela efanayo nokutya kuLawulo lokuTya kunye noLawulo lweziyobisi.

Kusemthethweni ukuba nabani na athenge kwaye asebenzise isongezelelo se-9-Me-BC. Ngaphandle koko, i-9-Me-BC ithathwa njengekhuselekileyo ngokwasemthethweni, kuyacetyiswa ukuba umntu abonane nogqirha ngaphambi kokuzifaka kuyo.

 

Iziphumo ebezingalindelekanga ze-9-Me-BC

Nangona i-9-Me-BC isongezelelo ithathwa njengekhuselekileyo, zimbini iziphumo ezinokubakho ze-9-Me-Bc.

Ifoto-ubuntununtunu -ukukhanya kwelanga ixesha elide kufuneka kuthintelwe xa usebenzisa 9-Me-BC isongezelelo njengoko oku kunokubangela umonakalo kwi-DNA ngenxa yokuvezwa kwemitha ye-UV. Ukuba kufuneka ube phantsi kwelanga i-sunscreen iyakufuneka ukuthintela iziphumo ebezingalindelekanga ze-9-Me-BC.

I-Dopamine neurotoxicity nayo inokwenzeka; Nangona kunjalo, oku kuyenzeka xa ugqitha idosi ye-9-Me-BC. Ke ngoko, kunokuthintelwa ngokuthatha idosi ye-9-Me-BC.

Ezinye iziphumo ebezingalindelekanga ze-9-Me-BC ezichazwe kubasebenzisi abelana ngamava abo e-9-Me-BC zibandakanya isicaphucaphu kunye neentloko. Nangona kunjalo, ezi ziphumo zibi zinqabile kwaye zenzeka kuphela xa umntu ethatha i-overdose yesongezelelo se-9-Me-BC.

 

Ngubani onokuxhamla kwi-9-me-bc (nootropic)?

Ngokusisiseko wonke umntu unokufumana izibonelelo ezivela kwi-9-Me-BC nootropic. Nangona kunjalo, amanye amaqela abantu anokuzuza ngakumbi kwi-9-Me-BC kunabanye. Abasebenzi, abafundi kunye neembaleki banokufumana isivuno esikhulu Izibonelelo ze-9-Me-BC.

Ukusukela, i-9-Me-BC ijikelezwe kakuhle kwaye ine-dopaminergic kakhulu, sisongezo esihle kakhulu kubafundi abafuna ukwandisa ukuphapha, inkuthazo yokufunda ngelixa bephucula ukufunda kwabo kunye nenkumbulo yokukhumbula ngakumbi.

Ukusebenza kunokuba noxinzelelo kunye nokufunxa, kodwa ngethamsanqa i-9-Me-BC inikezela inkuthazo kunye namandla akhulisa ukusebenza kwakho kakuhle. Ikhuthaza ii-neurons ezigcina ujonge kuyo yonke indlela.

Abasebenzisi bovavanyo lwe-9-Me-BC baqinisekile kakhulu ngaphandle okanye kweziphumo ebezingalindelekanga ezichaziweyo. Kungoko kulungile zongeza yabo bonke.

I-9-Me-BC

I-9-ME-BC powder ithengiswa-Uphi ukuthenga i-9-ME-BC?

I-9-Me-BC iyathengiswa ifumaneka ngokulula kwi-Intanethi. Nangona kunjalo, inqanaba eliphezulu lobumsulwa kufuneka uqiniseke ukuba ufumana iziphumo ezilindelekileyo. Qwalasela uphononongo lwe-9-Me-BC olusuka kubasebenzisi ukufumana ukuqonda kweyona capsule ye-9-Me-BC ilungileyo okanye izongezo zepowder.

Njengolunye uxhaso, kulungile ukuthatha ingqalelo kwimingcipheko ye-9-Me-BC enokuthi yenzeke kwaye ithathe amanyathelo okhuseleko afanelekileyo.

Abasebenzisi abaninzi be-9-Me-BC bayayithenga evunyiweyo abathengisi be-nootropics obonelela nge-9-Me-BC kwintengiso kumgangatho ophezulu kakhulu. 

Xa ucinga ukusebenzisa i-9-Me-BC thenga kwiinkampani ezibonelela nge-9-Me-BC ukuze ithengiswe ngesixa esikhulu ukuze wonwabele amaxabiso ezaphulelo.

Ucaphulo
  1. UGille G., Gruss M., Schmitt A., Braun K., Enzenperger C., Fleck C. kunye noAppenroth D. (2011) 9-Methyl-b-carboline iphucula ukufunda kunye nememori kwiigundane. Neurodegen. Dis. Ngomhla wesi-8, 195.
  2. Gruss, M., Appenroth, D., Flubacher, A., Enzenperger, C., Bock, J., Fleck, C.,… UBraun, K. (2012). Ukuphuculwa kwengqondo kwengqondo ye-9-Methyl-β-carboline inxulunyaniswa namanqanaba aphakamileyo e-hippocampal dopamine kunye nokwanda kwe-dendritic kunye ne-synaptic. Ijenali ye-Neurochemistry, 121 (6), 924-931.ikhonkco: 10.1111 / j.1471-4159.2012.07713. x.
  3. UHamann, J., Wernicke, C., Lehmann, J., Reichmann, H., Rommelspacher, H., kunye noGille, G. (2008). I-9-Methyl-β-carboline up-ilawula ukubonakala kwe-dopaminergic neurones eyahlukileyo kwinkcubeko ye-mesencephalic ephambili. I-Neurochemistry yamanye amazwe, i-52 (4-5), i-688-700.ikhonkco: 10.1016 / j.neuint.2007.08.018.
  4. I-Polanski W., Enzenperger C., Reichmann H. kunye noGille G. (2010) Iipropathi ezikhethekileyo ze-9-methyl-beta-carboline: ukukhuthaza, ukukhusela kunye nokuhlaziya ii-neurons zedopaminergic kunye neziphumo ezichasayo. J. Neurochem. 113, 1659-1675.
  5. UWernicke, C., Hellmann, J., Ziêba, B., Kuter, K., Ossowska, K., Frenzel, M.,… URommelspacher, H. (2010). I-9-Methyl-b-carboline ineziphumo zokubuyisela kwisimo sesilwanyana sesifo sikaParkinson. Iingxelo ze-Pharmacological, 19.
  6. UMBUTHO WESITHUBA SAMANDLA 9-METHYL-9H-BETA-CARBOLINE (2521-07-5)

 

Contents