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I-Nicotinamide Mononucleotide (NMN) i powder (1094-61-7)

I-Raw Nicotinamide Mononucleotide (i-NMN) i-powder egxininisiweyo yokuxhomekeka komzimba ......


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum
Amandla: 1370kg / inyanga

inkcazelo

Ividiyo ye-Nicotinamide Mononucleotide (NMN) ye powder (1094-61-7) ividiyo

I-Nicotinamide Mononucleotide (NMN) i powder (1094-61-7) Inkcazelo

I-Nicotinamide Mononucleotide powder ("NMN" kunye ne "β-NMN") iyinucleotide evela kwi-ribose ne-nicotinamide. Njenga-nicotinamide riboside, i-NMN iyimvelaphi ye-niacin, kwaye abantu baneenzyme ezingasebenzisa i-NMN ukuvelisa i-nicotinamide adenine dinucleotide (i-NADH).

Ngenxa yokuba i-NADH yintsebenziswano kwiinkqubo ngaphakathi kwe-mitochondria, ii-sirtuins, kunye ne-PARP, i-NMN iye yafundiswa kwiimpawu zezilwanyana njenge-neuroprotective ne-anti-aging agent. Iinkampani zenkxaso yokutya zithengisa ngokugqithiseleyo iimveliso ze-NMN zifuna ezo zinzuzo, nangona kungekho zifundo zonyango kubantu abashicilelwe okwamanje.

I-Raw Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Iinkcukacha

Igama lemveliso I-Nicotinamide Mononucleotide (NMN)
Igama leKhemikhali I-Beta-nicotinamide ribose monophosphate; Iphunga leNicotinamide Mononucleotide; AC1Q6RVF; AC1L23AN; I-NMN (+); SCHEMBL6858129
uhlobo Numama Mirailabo
Iqela leziyobisi Ukutya okuncedisayo
Inani leCAS 1094-61-7
InChIKey I-DAYLJWODMCOQEW-TURQNECASA-N
I molecular Fi-ormula C11H15N2O8P
I molecular WSibhozo 334.22
IMasaisotopic Mass 335.229 g / mol
Ukuxuba Point > 96 ° C
Fukuhlaziywa kwakhona Point Akukho mhla okhoyo
I-Biological Half-Life Ngaloo ndlela, njengoko kuboniswe kumzekeliso 3, i-nicotinamide yanyamalala egazini kunye nobomi bemizuzu yeeyure ze-5.3, kanti i-half-life of nicotinic acid yayiyiyure le-1.1.
umbala Umhlophe ukuya kutsho-omhlophe
Sukufaneleka I-Methanol (Kancinci), Amanzi (Kancinci)
Sisibetho Tukushisa I-Hygroscopic, -20˚C Ifreezer, phantsi kwe-Inert atmosphere
Aukuguquka Ukuze udlale indima yokwandisa ubomi kunye nokuphathwa kwesifo sikashukela

NamaNicotinamide Mononucleotide (NMN) powder (1094-61-7) Inkcazelo

I-Nicotinamide Mononucleotide powder ("NMN" kunye ne "β-NMN") iyinucleotide evela kwi-ribose ne-nicotinamide. Njenga-nicotinamide riboside, i-NMN iyimvelaphi ye-niacin, kwaye abantu baneenzyme ezingasebenzisa i-NMN ukuvelisa i-nicotinamide adenine dinucleotide (i-NADH).

Uphando olutsha luchaza ukuba i-NMN inokubuyisela imetabolism yeselula, ibe nefuthe eliphambili lokuguga. Eqhubekayo ngokwemvelo emzimbeni, i-NMN (β-Nicotinamide mononucleotide) ibaluleke kakhulu ekuguquleni izondlo kumandla. Ukuxhaswa kwe-NMN njengenxalenye yolawulo lwakho lwemihla ngemihla kunokunika amandla okuvuselela amandla, ukukhusela kwinkqubo yokuguga, kunye nokunciphisa umngcipheko weengxaki ze-cardiovascular. I-NMN i-cofactor kwimpendulo ye-redox, inkqubo ebalulekileyo ekusebenzeni komzimba kwisakhiwo se-ATP i-molecule ye-power supply ephakamileyo. I-NMN iqulethe i-Sirtuin esebenzayo iqela elikhuthaza ukuchaneka kwemitha kunye nokuphila ixesha elide.

Ukusetyenziswa kweNicotinamide Mononucleotide (NMN) powder (1094-61-7)

  1. I-Nicotinamide mononucleotide kwiiseli zabantu yenza indima ebalulekileyo ekuvelweni kwamandla, kubandakanyeka kwi-NAD ye-intracellular (i-nicotinamide adenine dinucleotide, ukuguqulwa kwamandla e-cell coenzyme ebalulekileyo), isetyenziselwa ukuguga, ukuwa ushukela wegazi kunye neminye imveliso yonyango.
  2. I-Nicotinamide Mononucleotide yi-vitamin e-soluble yamanzi, Umkhiqizo uphephu omhlophe wesikristalline, ungenasiphelo okanye ungasondelanga, unomonde, unomsoco, ungenakuncibilika emanzini okanye kwi-ethanol, ungancibilika kwi-glycerin.
  3. I-Nicotinamide Mononucleotidepowderis kulula ukuyifumana ngomlomo, kwaye ingahanjiswa ngokubanzi emzimbeni, i-metabolites okanye iprototype engaphezu kwangoko ikhupha umchamo. I-Nicotinamide inxalenye ye-coenzyme I kunye ne-coenzyme II idlala indima yokuhambisa i-hydrogen kwi-oxidation ye-oxidation ye-oxydation chain, inokukhuthaza iinkqubo ze-biological oxidation kunye ne-tissue metabolism, kugcina izicubu eziqhelekileyo (ingakumbi isikhumba, indlela yokutya kunye nenkqubo ye-nervous) inendima ebalulekileyo.

Ukongezelela, i-nicotinamide inokuthintela kunye nokunyangwa kwebhokisi yenhliziyo, umsebenzi we-node kunye ne-anti-fast testal arhythmias, i-nicotinamide inokuphucula kakhulu intlawulo yenhliziyo kunye ne-atrioventricular block ebangelwa yi-verapamil.

benefits iNicotinamide Mononucleotide (NMN) powder (1094-61-7)

  • I-NMN ikhuthaza amandla eMetabolism - i-NAD + inceda ukuphazamisa ukutya njengotshani kumandla.
  • Ukukhuthaza Ubunono obuBomi kunye neCadiodiovascular Function.
  • Ukulungiswa kwe-DNA yokuguga - I-NAD + isetyenziselwa ukulungiswa kwemida yeDNA.
  • I-SIRTUIN Umququzeleli-NAD + iyadingeka ukuba iigeni zethu zokuphila ixesha elide lisebenze.
  • I-NMN i-COMPM esebenzisa i-Harvard Scientific ukuguqula ezinye iimpawu zenyama yokuguga kwimichiza eyaqala ukukhawuleza kwi-NAD.
  • Inyango ye-NMN ikhusela ukulimala kwengqondo ebuchotsheni
  • I-NMN Treatment ihlaziya ukukhubazeka kwengqondo
  • I-Nicotinamide mononucleotide inqanda ukusebenza kwe-JNK ukuguqula isifo se-Alzheimer
  • I-NMN inokubuyisela ukuqonda kwiikhompyutha ze-AD

Kunconywe uNicotinamide Mononucleotide (NMN) powder (1094-61-7) Isistim

Imilinganiselo ephakamileyo ephakanyisiweyo ye-Nicotinamide Mononucleotide powder ikhona phakathi kwe-250 - 1500 mg ngosuku.

I-NMN ibambelela ngokukhawuleza kwaye inomlinganiselo omncinci wobomi, ukwenzela ukugcina amanqanaba e-NAD + aphakamileyo kangangokuthi kunokwenzeka kangangoko kunokwenzeka ukuba uthathe i-125 mg capsule ekuvukeni nomnye ngemini xa uthatha i-250 mg ngosuku.

Imiphumela iNicotinamide Mononucleotide (NMN) powder (1094-61-7)

Nangona i-Nicotinamide mononucleotide (i-NMN) ipowder yongezwa ngokutsha kwaye uphando luqhubeka, uphando olwenziwe ngoku lubonise ukuba lukhuselekile kwaye aluyiyo into enobuthi.

Imiphumo engabonakaliyo, kodwa utywala, isisu, isifungo, kunye nesisulu sezinto zibikwe kwezinye iimeko.


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Iziqulatho kunye nokuqulunqwa kwemveliso

I-2019 Latest Anti-Aging Imithi: I-Nicotinamide Mononucleotide (i-NMN)

Ucaphulo

  1. I-Mills, KF, Yoshino, J., Yoshida, S., et al. (2016). Ulawulo lwexesha elide lweNicotinamide Mononucleotide luthintela ukuNciphisa kwePhysiological kwi-Pice. Cell Metabolism.
  2. Yoshino, J., Mills, KF, Imai, SI, kunye neYoon, MJ (2011). I-Nicotinamide Mononucleotide, i-NAD + ephakathi, isebenzise i-Pathophysiology ye-Diet- ne-Age-Taked Diabetes kwi-Imice. Cell Metabolism.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., no-Sadoshima, J. (2014). I-Nicotinamide Mononucleotide, isiPhakathi seNAD + Synthesis, ikhusela iNhliziyo esuka kwi-Iskemia kunye nokuPhinda kwakhona.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, noMorris, MJ (2016). Intloko yeNtloko ngokuthelekiswa kweNtshukumo yesikhashana esifutshane neNAD pre-node + uNothanide Mononucleotide (i-NMN) kunye neeveki ezintandathu zoVavanyo lweeNtshontsho eziSetyhini.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., et al. (2019) Slc12a8 yiNicotinamide Mononucleotide Transporter. Uhlobo lweMetabolism.
  6. De Picciotto, NE, Mills, KF, Imai, S., Gano, LB, et al. (2016). I-Nicotinamide Mononucleotide ibuyisela i-Vascular Dysfunction kunye noxinzelelo lwe-Oxidative nge-Ping Agice.
  7. Yao, Z., Gao, Z., uYang, W., noJia, P. (2017). I-Nicotinamide Mononucleotide Inqanda i-JNK Ukuqalisa ukuguqula izifo ze-Alzheimer.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., et al. (2018). I-NAD + I-Supplementation i-Normalizes Iimpawu eziphambili ze-Alzheimer kunye ne-DNA Impendulo yokulimala kwi-AD entsha yeMouse Model kunye ne-Introduced DNA Repair Repair.

I-Shangke Chemical yinkampani ephakamileyo yezobuchwepheshe echanekileyo kuma-intermediate asebenzayo (APIs). Ukulawula umgangatho ngexesha lokuvelisa, inani elikhulu labaqeqeshi abanolwazi, izixhobo zokuvelisa iikholeji zokuqala kunye nama-laboratories ngamanqaku aphambili.

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