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I-Raw Compound i-7P powder (1890208-58-8)

Ipowuni ye-7p yenziwe yile ngqungquthela yamacandelo ngenjongo yokuchonga i-thromboxane ye-double acting .......


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum
Amandla: 1145kg / inyanga

inkcazelo

I-Raw Compound 7P powder (1890208-58-8) ividiyo

I-Raw Compound i-7P powder (1890208-58-8) inkcazelo

I-Raw Compound i-7P powder ekhuthaza ukuphuma kwe-neurite ye-neurons eziphambili ezikhuselweyo ezivela kwi-hippocampus, i-cortex ye-cerebral, ne-retina. kwisimo sezilwanyana sokulimala kwentsholongwane ye-optic, i-Raw Compound i-7P powder iboniswe ukunyusa ukukhula kwe-43 axx ax positive, ebonisa ukuba i-vitro neurite yomsebenzi we-Raw Compound 7P powder iguqulela ekuvuseleleni ukuhlaziywa kwe-axon kwi-vivo. I-Raw Compound i-7P powder kunye nokucaciswa kweendlela ezenza ukuba i-axon ivuselelwe kwi-vivo iya kunika ingqiqo kwiimvavanyo ezizayo zokuphucula izicwangciso zonyango.

ekrwada 2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide (iCompound 7P) powder (1890208-58-8) Suqobo

Igama lemveliso 2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide (i-Raw Compound 7P powder)
Igama leKhemikhali 2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide (i-Raw Compound 7P powder)
uhlobo Numama I-Raw Compound 7P powder
Iqela leziyobisi Izidakamizwa zeNootropic
Inani leCAS 1890208-58-8
InChIKey NAXWKPFXCOBXLE-UHFFFAOYSA-N
I molecular Fi-ormula C22H23N3O5S
I molecular WSibhozo 441.508g
IMasaisotopic Mass 440g / mol
Indawo yokunyibilika N / A
Fukuhlaziywa kwakhona Point N / A
I-Biological Half-Life N / A
umbala Powder
Sukufaneleka idibeneyo emanzini nakwi-ethanol.
Sisibetho Tukushisa Gcina kwiqondo lokushisa lokubanda, kwisitya esitywinwe, thintela ubushushu obukhulu kunye nokukhanya.
Aukuguquka • Ukwandisa ulungelelaniso
• Ukuphucula imvakalelo
• Unceda ukulwa nokukhathala
• Ukuthintela i-oxidation ngaphakathi kwengqondo
• Ukuphatha umonakalo owenziwe ngotywala

ekrwada ICandelo 7P powder (1890208-58-8) Inkcazelo

I-Raw Compound 7P (2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide) ikhupha i-neurite ephuma kwi-neurons ephakamileyo ekhusweyo evela kwi-hippocampus , i-cortex cortex, kunye ne-retina. kwisimo sezilwanyana sokulimala kwentsholongwane ye-optic, i-Raw Compound i-7P powder iboniswe ukunyusa ukukhula kwe-43 axx ax positive, ebonisa ukuba i-vitro neurite yomsebenzi we-Raw Compound 7P powder iguqulela ekuvuseleleni ukuhlaziywa kwe-axon kwi-vivo. I-Raw Compound i-7P powder kunye nokucaciswa kweendlela ezenza ukuba i-axon ivuselelwe kwi-vivo iya kunika ingqiqo kwiimvavanyo ezizayo zokuphucula izicwangciso zonyango.

Ukusetyenziswa kweCompound 7P powder (1890208-58-8)

I-7p (2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide) ibonise umsebenzi ophezulu kumaseli omhlaza wesibeletho. Kwimouse engabonakaliyo yexenograft imodeli ene-cell i-HeLa, i-7p ibonise ukukhuselwa komthamo wokhuhlane lwebele. Uviwo lwakhe lwama-tissue ephethe i-tumor lubonisa ukuba i-7p iphuculise i-microstructure ngendlela exhomekeke kumthamo. I-7p iComputer iphinde yandise inani lee-HeLa kwii-G0 / G1 kunye neS-isigaba kwaye iyancipha kakhulu ukuba isigaba seG2 / M. Imiphumo ye-7p kwi-C-caspase-3, i-C-caspase-9, i-BCl-2 kunye ne-Bax ibinzana kwi-HeLa iiseli zazimisela.

Ucwaningo lwe-Tubulin polymerization, i-immunofluorescence studies, uhlalutyo lwesigxina kunye novavanyo olukhuphisanayo lwe-tubulin-binding lwalubonisa ngokucacileyo ukuba i-7p iyindawo yokubopha i-colchicine kwindawo yokubopha i-tubulin.

benefits of ICandelo 7P powder (1890208-58-8)

I-7p yeComputer ivuselelwe ukuvuselelwa kwe-optic echotshoziweyo

Lungisa umonakalo wentloko

kucetyiswa ICandelo 7P powder (1890208-58-8) Isistim

IComple 7p ibonise i-100% inhibition of pesasemia ngosuku lwe-4 kumayeza amaninzi (i-100, i-50, ne-25 mg / kg) enikezelwa iintsuku ezine ezilandelelanayo, kodwa kwi-100 mg / kg, zonke iigundane zasinda kwaye zaphiliswa, ngelixa i-50 mg / kg, ezintathu zintlanu zisaphila kwaye iipilisi ezimbini zaphiliswa, kwaye kwi-25 mg / kg, akukho namagundane asinda


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