Anandamide (AEA) (94421-68-8)

Matshi 15, 2020
SKU: 77472-70-9
5.00 ngaphandle kwe 5 ngenxa ye 1 ireyithingi abathengi

I-Anandamide, ekwabizwa ngokuba yi-N-arachidonoylethanolamine (AEA), yi-fatot acid neurotransmitter evela kwi …………… ..


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum

Anandamide (AEA) (94421-68-8) ividiyo

Anandamide (AEA) (94421-68-8) Suqobo

Igama lemveliso Anandamide (AEA)
Igama leKhemikhali I-Arachidonylethanolamide; N-Arachidonoylethanolamine; Anandamide (20.4, n-6);

N-Arachidonoyl-2-hydroxyethylamide; Arachidonoyl ethanolamide; AEA;

Inani leCAS 94421-68-8
InChIKey I-LGEQQWMQCRIYKG-DOFZRALJSA-N
SMILE CCCCCC = CCC = CCC = CCC = CCCCC (= O) NCCO
I-Molecular Formula C22H37NO2
Isisindo somzimba 347.53
IMasaisotopic Mass 347.282429 g / mol
Indawo yokunyibilika N / A
Point yo kubilisa 522.3 ± 50.0 ° C (Kuxelwe kwangaphambili)
mninzi I-0.92 g / mL kuma-25 ° C (ilitha)
umbala ophuzi okhanyayo
Sitempile yetanki -20 ° C
Umzimba I-ethanol: inyibilika
isicelo Isetyenziselwa imemori, ukushukumiseka, iinkqubo zengqondo, ulawulo lwentshukumo, ulawulo lweentlungu, umdla wokuvuselela umdla kunye nokuzala.

Yintoni i-Anandamide (AEA)?

I-Anandamide, ekwabizwa ngokuba yi-N-arachidonoylethanolamine (AEA), yi-fatty acid neurotransmitter ethathwe kwi-non-oxidative metabolism ye-eicosatetraenoic acid (arachidonic acid. Inesakhiwo esifana kakhulu ne-tetrahydrocannabinol, indawo esebenzayo ye-cannabis. ichithwe ngokuyintloko yi-encyme enamafutha acid amide hydrolase (i-FAAH), eguqula i-anandamide kwi-ethanolamine kunye ne-arachidonic acid, Ekugqibeleni, i-Anandamide yenzelwe i-neuron ngokusabela komgaqo kwenzeka phakathi kwe-arachidonic acid kunye ne-ethanolamine phantsi kommiselo we-calcium ion kunye ne-cyclic monophosphate adenosidase. Lisanduleli seqela lezinto ezisebenza ngokwasemzimbeni (Prostamides) ezidlala indima kwimisebenzi emininzi yomzimba, kubandakanya ukuthanda ukutya, inkumbulo, iintlungu, uxinzelelo kunye nokuzala .. Ukongeza, i-Anandamide ikwathintela abantu Ukunyuka kweeseli zomhlaza webele.

I-Anandamide ikhona kwizinto ezininzi, ezinje nge-urchin yolwandle, ubuchopho behagu kunye neempuku zemithambo, njl, kodwa inani labo lincinci. Kwakhona, abaphandi bafumanise i-Anandamide kunye nezinto ezimbini (i-N-oleoylethanolamine kunye ne-N-Linoleylethanolamine) kwitshokholethi emnyama. I-Anandamide ikho nakwimimandla esetyenzisiweyo,

Njengenxalenye yenkqubo ye-endocannabinoid (ECS), i-Anandamide ichongwa njengomlawuli we-homeostasis kunye nolunye udidi lwe-cannabis-efana ne-2-AG ye-cannabinoid receptors emzimbeni wonke. Le nkqubo ikhona kuzo zonke iirtebrates. I-Anandamide idlala indima yokulawula indlela yokutya kunye neurogenic yenkuthazo kunye nolonwabo, ukugcina imizimba yethu kunye nengqondo zilungelelene. Izifundo zifumene ukuba iimvakalelo zethu, ulonwabo, uloyiko, ixhala, kunye nokukwazi ukumelana noxinzelelo zonke zilawulwa yinkqubo ye-endocannabinoid, kunye nezifo ezahlukeneyo ukusuka kwi-schizophrenia ukuya kuxinzelelo zihamba kunye namanqanaba angaqhelekanga e-anandamide.

I-Anandamide, efana ne-THC, yi-agonist yenxalenye ye-CB1R. Inokubangela ukuphuculwa okunokubakho ngokuthi kusebenze "ngokupheleleyo" kwinkqubo yengqondo. Kuya kufuneka ukuba uqaphele ukuba zonke ezi ziphumo ze-Anandamide zibonakala ngathi ziphuculwe yi-pharmacologic ekuthinteleni ukonakaliswa kwayo kwe-metabolic. Ukufunyanwa kuka-Anandamide kunokukhokelela kuphuhliso losapho olutsha lwamachiza onyango.

Izibonelelo ze-Anandamide (AEA)

I-Anandamide, eyaziwa ngokuba yi- "bliss molecule", isisimamisi esimanyumnyezi, isifo seengcongconi, kunye ne-endocannabinoid, enezibonelelo ezininzi zempilo nezengqondo:

I-Anandamide inciphisa ukwakhiwa ngokukhawuleza kweeseli zomhlaza. Ngo-1998, iqela leenzululwazi zase-Italiya lafumanisa ukuba i-anandamide inokunyusa i-neurogeneis kwaye yenze iiseli zemithambo emitsha, ngokuthe ngcembe ukwakheka / ukunyusa ixabiso leseli yomhlaza webele.

Amandla ka-Anandamide okukhuthaza i-neurogeneisis (ukwakheka kwee-neurons ezintsha) idlala indima kulawulo lokuziphatha lokuziphatha kunye nokuvelisa inkuthazo kunye nolonwabo kwiimpuku. Oku kunceda ukunciphisa iimpawu zoxinzelelo kunye noxinzelelo. Isifundo kwi-2015 yabantu kunye neempuku zifumene ukuba amanqanaba aphezulu e-anandamide anokukhuthaza ukuphuculwa kwemood kunye nokunciphisa ukunciphisa.

Ukongeza, ukukwazi kwe-anandamide ukubopha kwi-CB1 kunye ne-CB2 receptors kuya kuchaphazela kakhulu iindlela zokusebenza komzimba, kubonakalisa izibonelelo ezilungileyo ngokubhekisele kwimemori, ukukhuthaza, iinkqubo zengqondo, ukulawulwa kokuhamba, ukulawula iintlungu, ukuvuselela umdla kunye nokuzala.

Ungayonyusa njani i-anandamide(AEA) amanqanaba emzimbeni womntu?

Ngenxa yokuba i-anandamide inendima ye-neurotransmitter, iarhente ye-vasodilator kunye ne-serum metabolite yegazi lomntu, kunye nezibonelelo zezempilo kunye nezengqondo ezibonisiweyo, unokufuna ukwandisa inqanaba le-anandamide emzimbeni wakho. Nazi ezinye zeendlela zokwandisa amanqanaba e-anandamide okwethutyana emzimbeni womntu:

- Imithamboba

Uphononongo lufumanise ukuba emva kwemizuzu engama-30 yokubaleka kuphela, umxholo we-anandamide (AEA) wabantu kunye nezinja wanda. Ke ukuba ufuna ukufumana isibonelelo, yenza umthambo rhoqo rhoqo.

-Ukutya itshokholethi emnyama

Itshokolethi emnyama inenxalenye ephezulu ye-theobromine kwitshokholethi esempilweni, kwaye i-theobromine inceda ukwandisa imveliso ye-anandamide kwingqondo kwaye iye icothise ukuwohloka kwayo okwethutyana.

- Ukutya i-truffle emnyama

I-truffle emnyama (isikhunta esimnyama) ngokwemvelo iqulethe i-anandamide. Nangona le fungus ingenako ukusebenzisa i-anandamide nangayiphi na indlela, abaphandi bakholelwa ukuba isetyenziselwa ukutsala izilwanyana ukuba ziyitye kwaye ivelise kwakhona amabala ayo.

-Ukufumana ingqwalaselo

Uphando lubonisa ukuba xa umntu ekwimeko (ebizwa ngokuba "flow" okanye "kwingingqi,") yoxinzelelo oluphezulu, intsebenzo, kunye noxinzelelo, ayisiyi kuba nemveliso ngakumbi okanye udale imisebenzi engcono kwingqondo yakho. Inani elikhulu leekhemikhali, ezinje nge-serotonin, dopamine, endorphin kunye ne-anandamide.

Ngaphezu koko, iti, i-coriander kunye ne-celery inokunceda ukwandisa imveliso ye-anandamide.

Imbekiselo:

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