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I powder Orlistat emfutshane (96829-58-2)

I-powder Orlistat ebomvu iyisisetyenziswa esisetyenziswa kunyango lokunyanya. Umsebenzi walo oyintloko ukhusela ukuxutywa kwamafutha ekudleni kwabantu ....


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum
Amandla: 1470kg / inyanga

inkcazelo

I powder OrLood (96829-58-2) ividiyo

I powder Orlistat emfutshane (96829-58-2)

I-powder Orlistat ephakamileyo kwinqanaba lemithi ebizwa ngokuthi i-lipase inhibitors esebenza ngokuvimbela ukunyuka kwe-25% yeenqatha ekudleni kwaye isetyenziselwa ukulahleka kwesisindo kubantu abadala abangaphezu komzimba, iminyaka engama-18 nangaphezulu, xa isetyenziswe kunye ne-calori eyancitshisiwe kunye ukutya okuncinci. I-powder Orlistat ephuhlileyo isilwanyana esilungiselelwe ukunyanyisa ukukhuluphala. Umsebenzi walo oyintloko ukhusela ukuxutywa kwamafutha ekudleni kwabantu, ngaloo ndlela ukunciphisa i-caloric intake. I-powder Orlistat ebomvu isebenza ngokuvimbela i-pancreatic lipase, i-enzyme ephula i-triglycerides emathumbu. Ngaphandle kwale enzyme, i-triglycerides esuka ekudleni iyakhuselwa ekubeni i-hydrolyzed ibe yi-fatty acids free acids kwaye ixutywe ngaphandle. I-Orlistat yomdaka ogqityiweyo wesigqirha isetyenziselwa abantu abangaphezu kwamandla amaninzi abangase babe negazi eliphezulu, isifo sikashukela, i-cholesterol ephezulu okanye isifo senhliziyo. Ukusebenza kwePowula okanye i-Orlistat powder ekunyuseni ukulahlekelwa kwesisindo kucacileyo kodwa kuthobekile. Idatha edibeneyo evela kwizilingo zeklinikhi ibonisa ukuba abantu banikezwa i powder Orlistat powder ngaphezu kwendlela yokuphila yokuguqulwa, njengokutya kunye nokuzilolonga, balahlekelwa malunga ne-2-3 kilogram (i-4.4-6.6 lb) ngaphezu kwalabo abangathathi iziyobisi ngaphezu kwexesha lonyaka. I-Orlistat powder i-Rawdat iyanciphisa ngokunyanisekileyo uxinzelelo lwegazi kwaye ibonakala ithintela ukuqala kohlobo lwe-2 sikashukela, nokuba sisuka kwindleko yesisindo ngokwaso okanye ezinye iziphumo. Iyanciphisa iziganeko zesifo sikashukela sohlobo II kubantu abanobukhulu besantya esilingana nomlinganiselo ofanayo wokuphila.

I powder Orlistat emfutshane (96829-58-2) Iinkcukacha

Igama lemveliso I-powder Orlistat
Igama leKhemikhali Tetrahydrolipstatin, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate
uhlobo Numama Alli, Xenical
Iqela leziyobisi lipase inhibitors
Inani leCAS 96829-58-2
InChIKey AHLBNYSZXLDEJQ-FWEHEUNISA-N
I molecular Fi-ormula C29H53NO5
I molecular WSibhozo 495.745 g / mol
IMasaisotopic Mass 495.392 g / mol
Ukuxuba Point <50 ° C
Fukuhlaziywa kwakhona Point Akukho mhla okhoyo
I-Biological Half-Life Ngokusekelwe kwidata elinganiselwe, isigamu-ubomi se-Raw Orlistat powder ingxowankulu kwi-1 kwiiyure ze-2.
umbala Powder
Umzimba I-DMSO: 19 mg / mL
yoGcino Tukushisa Ixesha lokugcina. 2-8 ° C
Aukuguquka Sebenzisa ukunyanyisa ukukhuluphala.

Uluhlu oluthile i powder (96829-58-2) Inkcazo

I-powder Orlistat ephakamileyo kwinqanaba lemithi ebizwa ngokuthi i-lipase inhibitors esebenza ngokuvimbela ukunyuka kwe-25% yeenqatha ekudleni kwaye isetyenziselwa ukulahleka kwesisindo kubantu abadala abangaphezu komzimba, iminyaka engama-18 nangaphezulu, xa isetyenziswe kunye ne-calori eyancitshisiwe kunye ukutya okuncinci.

I-powder Orlistat ephuhlileyo isilwanyana esilungiselelwe ukunyanyisa ukukhuluphala. Umsebenzi walo oyintloko ukhusela ukuxutywa kwamafutha ekudleni kwabantu, ngaloo ndlela ukunciphisa i-caloric intake. I-powder e-Orlistat ebomvu isebenza ngokuvimbela i-pancreatic lipase, i-enzyme ephula i-triglycerides emathumbu. Ngaphandle kwale enzyme, i-triglycerides esuka ekudleni iyakhuselwa ekubeni i-hydrolyzed ibe yi-fatty acids free acids kwaye ixutywe ngaphandle. I-Orlistat yomdaka ogqityiweyo wesigqirha isetyenziselwa abantu abangaphezu kwamandla amaninzi abangase babe negazi eliphezulu, isifo sikashukela, i-cholesterol ephezulu okanye isifo senhliziyo. Ukusebenza kwePowula okanye i-Orlistat powder ekunyuseni ukulahlekelwa kwesisindo kucacileyo kodwa kuthobekile. Idatha edibeneyo evela kwizilingo zeklinikhi ibonisa ukuba abantu banikezwa i powder Orlistat powder ngaphezu kwendlela yokuphila yokuguqulwa, njengokutya kunye nokuzilolonga, balahlekelwa malunga ne-2-3 kilogram (i-4.4-6.6 lb) ngaphezu kwalabo abangathathi iziyobisi ngaphezu kwexesha lonyaka. I-Orlistat powder i-Rawdat iyanciphisa ngokunyanisekileyo uxinzelelo lwegazi kwaye ibonakala ithintela ukuqala kohlobo lwe-2 sikashukela, nokuba sisuka kwindleko yesisindo ngokwaso okanye ezinye iziphumo. Iyanciphisa iziganeko zesifo sikashukela sohlobo II kubantu abanobukhulu besantya esilingana nomlinganiselo ofanayo wokuphila.

Orlistat powder (96829-58-2) Indlela yokuSebenza

I-Orlistat powder iyinhlobo ye-lipase yokuvimbela ukulahlekelwa kwesisindo semfuyo kwaye i-hydrated derivative ye -postpost. I-Orlistat ngempumelelo kwaye ikhetha ukuvimbela i-lipase yesisu kunye ne-pancreatic lipase, ngelixa ingaba nefuthe kwezinye i-enzyme zokutya (ezifana ne-amylase, trypsin kunye ne-chymotrypsin) kunye ne-phospholipase, kwaye ayichaphazeli ukuxutywa kwe-carbohydrate, iprotheni kunye ne-phospholipids. Eli gciwane alixakwanga nangona i-tractinal tractinal and has a effect reversible effect on lipase. I-Orlistat ikhubaza i-enzymes ngokuzibophelela ngokukhawuleza kwiindawo zokuhlala zesithensi kwiindawo ezisebenzayo zesisu ne-pancreatic lipase. Oku kuvimbela amanqatha ekudleni ukuba aphule kwi-fatty acid acids kunye ne-diacylglycerol, ngoko ayikwazi ukuxhamla, ukunciphisa i-caloric intake kwaye ngoko ke ukulawula umzimba. Esi sidakamizwa asikho isidingo sokuba sithathwe ngumzimba wonke ukuba siphumelele. Umsebenzi we-Orlistat we-pharmology ngumxholongwane oxhomekeke kuwo: i-Orlistat yonyango (i-120mg / d, i-tid, esithathwe ngokutya), idibene ne-calorie ephantsi, inokunciphisa i-30% ye-fat absorption. Kwisifundo ngokuthelekisa izisebenzi zokuzithandela eziqhelekileyo, i-Orlistat yayingabandakanywa ngumzimba nonke kwaye ibe nexinzelelo legazi eliphantsi kakhulu. Emva komlinganiselo omnye womlomo (i-800mg enkulu), ukuxilongwa kwegazi lwe-Orlistat kule ilandelayo iiyure ze-8 kwakukho <5 ng / ml. Ngokuqhelekileyo, imilinganiselo yonyango ye-Orlistat ixhaswa ngumzimba kuphela kwaye ayiyi kuqokelela kwixesha elifutshane lonyango. Kuvavanyo lwe-in vitro, i-Orlistat yezinga lokubopha kunye nezinye iiprothini ze-serum zidlulile i-99% (iiproteni ezibophekileyo ziyi-lipoproteins kunye ne-albumin), kunye nezinga lokubopha kunye neeseli ezibomvu zegazi zaziphantsi kakhulu.

Iinzuzo ze-Orlistat powder (96829-58-2)

▪ I-Orlistat iyanciphisa umzimba ubuninzi ngaphezu kwe-20% kwiindleko zomzimba

▪ I-Orlista ikunceda ufunde indlela yokubala iekhalori

▪ I-Orlista ikunika umvakalelo wokuphila

▪ I-Orlista ineempembelelo ezilungileyo zinika ithemba kunye nolonwabo kubasebenzisi

▪ I-Orlista inikeza iziphumo ezizinzileyo zexesha elide

▪ I-Orlista iyanciphisa ubunzulu bezifo ezinjenge-hypotension, isifo sikashukela, i-atherosclerosis kunye

i-cholesterol.

I-Orlistat ekhuthazwayo i powder (96829-58-2) Isisombululo

I-dose ephakanyisiweyo ye-Orlistat powder enye ye-120-mg capsule kathathu ngosuku kunye nesondlo ngasinye esisisiseko esineziqhamo (ngexesha okanye ukuya kwi-1 iyure emva kokutya). Amanani angaphezulu kwe-120 mg kathathu ngosuku ayengaboniswa ukuba anikezele inzuzo eyongezelelweyo.

Abantu kufuneka babe kwi-dietary balance, eyancitshisiwe-khalori equlethe malunga ne-30% yeekhalori kwioli. Ukutya kwamaxesha amaninzi, i-carbohydrate kunye neprotheni kufuneka kuhanjiswe ngaphezu kwezidlo ezintathu eziphambili. Ukuba isidlo silahleka ngezinye izihlandlo okanye siqulethe i-fat, i-dose ye-Orlistat powder ingashiywa.

Ngenxa yokuba i-Orlistat powder iboniswe ukunciphisa ukuxutywa kwamavithamini amaninzi kunye ne-betacarotene, abantu kufuneka bacebise ukuba bathathe i-multivitamin equkethe amavithamini anelumnyoli enomzimba ukuqinisekisa ukutya okwaneleyo. Ngaphandle, i-vitamin supplement kufuneka ithathwe ubuncinane kwiiyure ze-2 ngaphambi okanye emva kokulawulwa kwe-Orlistat powder, efana ngexesha lokulala.

Imiphumo emibi ye-Orlistat powder (96829-58-2)

Kuyinto eqhelekileyo ukuqaphela imiphumo emibi ye-Orlistat powder xa usisebenzisa. Unokufumana ezinye zeempembelelo okanye kungekhona nje emva kokuthatha nayiphina imithi. Uninzi lweziphumo eziza kunye nokusetyenziswa kwe-Orlistat powder zihlobene nendlela esebenza ngayo kwinkqubo yakho yokutya. Zivame ukuba zinyameko kwaye zenzeke rhoqo xa uqala unyango. Kwenzeka kwakhona emva kokuba uthathe isidlo esikhulu seoli. Ngenhlanhla, uninzi lwalo luya njengoko unyango luqhubeka kwaye emva kokulandela ukutya okulungileyo.

Ezi zilandelayo ziphumo zecala eziqhelekileyo:

intloko ebuhlungu

Iintlungu zesisu / ukuphazamiseka

Ukukhutshwa kwamanzi

Izitye

Ukugqithisa kwesikhumba esilula

Umqolo obuhlungu

Ngaphandle koko, ukuba uhamba nawuphi na wale miphumo emibi, kufuneka uyiphathise njengongxamiseko kwaye ugqirha ugqirha ngokukhawuleza. Bazi;

Intlungu ebuhlungu besisu esingahambi.

Ukuvuthwa okanye ukugqithisa ngokweqile

Unzima ukugwinya

Ukuphefumula okunzima


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Iziqulatho kunye nokuqulunqwa kwemveliso

I-Orlistat yokulahlekelwa kwesisindo: Sinokuyithatha njani inqabileyo?

isingqiniso

  1. Ukutyalwa kwamanzi kunye nokutywala, okuhlelwe ngu-Armand B. Christophe, uStephanie R. De Vriese, uStephanie DeVriese, iphepha 426- 437.
  2. Inkqubela yokuPhepha koMzimba: 9, ehleliwe nguGeraldo Madeiros-Neto, uAlfredo Halpern, uClaude Bouchard, iphepha le1046.
  3. Ukunyameka nokuLawula ubunzima bokuNakekelwa kwePrayimari-NguColin Waine, uNick Bosanquet, iphepha 68-71.

I-Shangke Chemical yinkampani ephakamileyo yezobuchwepheshe echanekileyo kuma-intermediate asebenzayo (APIs). Ukulawula umgangatho ngexesha lokuvelisa, inani elikhulu labaqeqeshi abanolwazi, izixhobo zokuvelisa iikholeji zokuqala kunye nama-laboratories ngamanqaku aphambili.

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