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I-Raw Synephrine powder (97-07-5)

I-Synephrine ngokwemvelo ikhona kwizityalo ze-citrus ezivela kwintsapho yaseRutaceae, yi-alkaloid sympathomimetic. I-Synephrine inezinto ezintathu ezahlukeneyo ......


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum
Amandla: 1370kg / inyanga

inkcazelo

I-Raw Synephrine powder (97-07-5) ividiyo

I-Raw Synephrine powder (97-07-5)

I-Raw Synephrine i-powder iyimichiza eyenziwa ngokwemvelo efunyenwe ngabadlali kunye nabafuna ukunyusa ubunzima ngenxa yemiphumo yayo kwimveliso yamandla yomzimba. Nangona kunjalo, eli qela linokuthi lisebenze njenge-antioxidant kunye ne-anti-inflammatory agent kwaye linokuba nezinye iimpawu zonyango ezibalulekileyo.

I-Raw Synephrine powder i-amine ye-biogenic. Itholakala kumanqanaba aphakamileyo kwiipelisi zezityalo ze-citrus, njenge-orange orange okanye i-orange orange (i-Citrus inurantium). Ukukhutshwa kweziqhamo okanye iipelisi zezi zityalo sele zisetyenzisiwe kwiyeza zamasiko zaseShayina ukuze ziphathe iingxaki zesisu kunye nokudlulela kwamakhulu eminyaka.

I-Raw Synephrine powder (97-07-5) Iinkcukacha

Igama lemveliso I-Raw Synephrine powder
Igama leKhemikhali Synephrine; Oxedrine; P-Synephrine ;; Parasympatol; Sympaethamine
uhlobo Numama Yocon
Iqela leziyobisi I-Fat ilahlekile
Inani leCAS 97-07-5
InChIKey YRCWQPVGYLYSOX-UHFFFAOYSA-N
I molecular Fi-ormula C9H13NO2
I molecular WSibhozo 167.208 g / mol
IMasaisotopic Mass 167.095 g / mol
Ukuxuba Point 162 ku-164 ° C
Point yo kubilisa 295.79 ° C (uqikelelo olunzima)
I-Biological Half-Life Akukho mhla okhoyo
umbala Umhlophe ukuya kutsho-omhlophe
Sukufaneleka Akukho mhla okhoyo
Sisibetho Tukushisa Ifriji
Aukuguquka Ngokuqinisekileyo iindawo ezivuthayo ezinqamlekileyo zatye

I-Raw Synephrine powder (97-07-5) Inkcazo

I-Synephrine, ebizwa nangokuthi, i-p-synephrin, ivela ngokwemvelo i-alkaloid. Inxalenye enkulu ye-agonists ye-adrenergic i-p-synephrin, kwaye ibhalwe kwi-pharmacopoeia evela kwiNtlaphu Yurophu kunye neJamani. Kukhoyo kwiimveliso ezichithwayo zezidakamizwa njenge-neo-synephrine, i-analog e-substitute. i-p-synephrine kunye ne-m-synephrine ziyaziwa ngokuba zihlala zihlala ziba neempembelelo ezixhatshaziweyo xa zifaniswa ne-norepinephrine. Ingasetyenziselwa unyango lwezonyango lwe-bronchial asthma, i-hypotension, ukuwa, ukuphazamiseka, kunye ne-hypotension; ukuphucula imetabolism; kunye nokunyanga kweengxaki zokugaya ukutya ezifana nokuhlengahlengisa, ukuvuvukala kwesibindi, i-phlegm kunye ne-ptosis.

Kwamazwe angaphandle, i-powder synephrine ipakishe ifunyenwe ngabagijimi kunye nalabo bafuna ukunciphisa umzimba ngenxa yemiphumo yamandla emzimbeni. I-Synephrine isetyenziselwa unyango lokunyanyisa ngokunyusa ukusetyenziswa kweekhalori kunye ne-oxidation ye-fat, kwakunye nokunciphisa uxinezeko olunefuthe olubangelwa ukukhuluphala. Nangona kunjalo, eli qela linokuthi lisebenze njenge-antioxidant kunye ne-anti-inflammatory agent kwaye linokunye okuncedo kwezempilo.

I-Raw Synephrine powder i-amine ye-biogenic. Itholakala kumanqanaba aphakamileyo kwiipelisi zezityalo ze-citrus, njenge-orange enomlilo okanye i-Orange orange (i-Citrus inurantium). Ukukhutshwa kweziqhamo okanye iipelisi zezi zityalo sele zisetyenzisiwe kwiyeza zamasiko zaseShayina ukuze ziphathe iingxaki zesisu kunye nokudlulela kwamakhulu eminyaka. Okwangoku, i-p-synephrin isetyenziswa ngokubanzi kwiyeza, ukutya, isiphuzo kunye namanye amashishini.

I-powder Synephrine (97-07-5) Indlela yokuSebenza

Imiphumo ye-cardiovascular of ligands ihambelana ne-adrenergic receptor ebophayo. Ngokubanzi, xa iigins zibophelela kwi-α-adrenergic receptors, i-vasoconstriction ivela, kwaye xa ibophezela kwi-receptors ye-β1-adrenergic, isivumelwano se-cardiovascular and increased heart rate. Izifundo zibonisa ukuba i-synephrine powder ibophezela kwi-β3-adrenergic receptors, okubangela ukwanda kwikhono lomzimba lokuphula amafutha. Ukubophelela kwi-β3-adrenergic receptors ayichaphazeli izinga lenhliziyo okanye uxinzelelo lwegazi. Kwakhona, ngenxa yokuba i-synephrine ibonakalisa encinci okanye ayikho into ebophekileyo kwi-α1-, i-α2-, i-β1-, ne-β2-adrenergic receptors kwaye ayibonakali ukuba yenze imiphumo engabonakaliyo, i-cardiovascular effects, njengokwanda kwenani lentliziyo kunye negazi, bafumana amayeza athile, ngokungafani nenani lezinye i-phenylethylamine kunye ne-phenylpropanolamine. Utshintsho oluthile lwezakhiwo lubangela ukubahluko omkhulu kwi-adrenergic receptor ibophe kwaye emva koko ikwazi ukuvelisa imiphumo ye-cardiovascular.

I-Synephrine iphinda ikhulise ukusetyenziswa komzimba we-carbohydrates ngokuvelisa amandla amaninzi ngendlela ye-ATP.49-52 Iququzelela ukufunyanwa kweglucose yamaseli, kunye ne-glycogenolysis, i-gluconeogenesis, i-glycolysis kunye ne-oxygen. Ukubandakanyeka kokubili i-calcium ion kunye ne -AMP ne-adrenergic receptors kuye kwaboniswa ukuba kubandakanyeke kule nkqubo ye-biochemical, kubonisa ukubandakanyeka kweendlela ezininzi.

Ngaphandle, ukusetyenziswa kwe-Synephrine powder kuyakuvimbela ukusebenza kwe-NF-kB. Le nto yinto ebalulekileyo ekubangela izifo ezinokubhubhisa ezifana ne-asthma. Ukusetyenziswa kweSynephrine kuye kwafunyanwa kuthintela isenzo se-eotaxin-1 hormone ngokubanzi. Oku kuvimbela ukunyuka kwe-eosinophil kwindawo echanekileyo.

Nangona kungangqiniswanga kakuhle ngokusebenzisa iimvavanyo, ukusetyenziswa kwe-Synephrine powder kuye kwafunyanwa ukuvimbela isenzo se-acetylcholinesterase. Le khemikhali iyaziwa ngenxa yesifo se-Alzheimer.

Ukusetyenziswa kwe-Synephrine powder (97-07-5)

▪ Ukuphucula ukusebenza komsebenzi

▪ Ukwelapha isifo sikashukela

▪ Uncedo ekunciphiseni ukulahleka

▪ Ukunciphisa ukwesaba ngaphambi kokuhlinzwa

▪ Ukwelapha izifo ezikhunjulwayo zesikhumba ezinjengeenkomo, unyawo lomdlali, kunye ne-jock itch.

▪ Ukuphucula iMood kunye neNqanaba lamandla

Ukuphakanyiswa kwe-Synephrine powder (97-07-5) Isisombululo

Amanqanaba asemgangathweni omzimba we-Synephrine powder yi-50-100mg imihla ngemihla kunye ne-30-40 imizuzu ngaphambi kokufunda. Kwaye, kuyona nto ibanjwe into yokuqala ekuseni okanye 15 - 30 imizuzu ngaphambi kokuzivocavoca. I-powder Synephrine kufuneka ithathwe ngamanzi ngaphambi kokuzivocavoca.

Izinzuzo ze-Synephrine powder (97-07-5)

♦ Uhlolisiso (DB-RCT) lamadoda e-12 lubonise ukuba ipileni ye-synephrine ithathe imizuzu ye-45 ngaphambi kokuzivocavoca kwandisa inani lokuphindaphinda kunye nomthwalo osisigxina xa usenza izikwere eziqhathaniswa ne-placebo.

♦ Uphando lwangaphambili lubonisa ukuba ukusela itiye eyenziwa ngamagqabi aseIndiya snakeroot kunye nesityalo se-orange enomsindo kwiinyanga ze-4 kubonakala kunciphisa izinga lokushukela egazini kubantu abanesifo sikashukela.

♦ Ukudibanisa i-synephrine, i-caffeine, ne-St. John's wort kunokuncedisa ukunciphisa umzimba xa kusetyenziswa ukutya okuncinci kwekhalori kunye nokuzivocavoca.

♦ Ufundo (i-DB-RCT) yezifundo ze-10 ezinikezwa i-50 mg ye-synephrin zibonise ukuba izifundo zatshisa i-65 calories ngaphezu kwabathathi-nxaxheba abaye banikezwa indawobo kwimizuzu yokuqala ye-75 emva kokuthatha isongezelelo.

♦ Uphando lubonisa ukuba ukuthatha iiyure ezimbini ezinomsoco ngaphambi kokuba unyango linciphise ukwesaba.

♦ Ioli ye-orange entle, equkethe i-synephrin ngaphezu kwezinye izithako ezisebenzayo, kwisifundo esinye sezigulane ze-60, ukuphucula izifo zesikhumba se-fungal (iinyawo, umzimba / isikhumba, okanye i-groin) kwi-2 kwii-3 kwiiveki ngaphezulu kwe-80% yabathathi-nxaxheba.

♦ Amagundane kunye neempawu zokuqala zokudakumba, kuquka iingxaki zokulala kunye nokutshintsha kwindlela yokutya, yenza okungakumbi xa usabela kwiziganeko ezixinzelelekileyo, njengokunyanzeliswa ukuba udide, kunokuba amagundane anempilo. Olunye uphando lubonise ukuba iigundane ezondla i-synephrine powderwere zinako ukuguqula ixesha elide, ezibonisa amandla aphezulu kunye namaqondo omninzi

♦ Uphononongo olunye lwama-laboratory lubonisa ukuba i-synephrine powder ivimbele ukukhula kwamabhaktheriya kuquka u-E. coli, obangela ukutyhelwa kokutya, kunye ne-Staphylococcus aureus, enokubangela izifo zesikhumba.

♦ Uhlolisiso olwenziwe ngokusebenzisa ihagu zeginea lubonisa ukuba i-synephrine yanciphise i-spinms ye-muscle ehamba phambili kwi-trachea, uphawu olunxulumene nokukhwehlela. U-Synephrine wanciphisa iimpawu ze-asthma ezenzekayo xa izilwanyana zanikwa i-histamines.

♦ Kwimichiza enobunzima bephunga, i-synephrine yanciphisa inani lamangqamuzana avuthayo kunye ne-cytokines ezivuthayo i-TNF-alpha kunye ne-IL-6, ngelixa likhula i-IL-10 echasayo.


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I-Shangke Chemical yinkampani ephakamileyo yezobuchwepheshe echanekileyo kuma-intermediate asebenzayo (APIs). Ukulawula umgangatho ngexesha lokuvelisa, inani elikhulu labaqeqeshi abanolwazi, izixhobo zokuvelisa iikholeji zokuqala kunye nama-laboratories ngamanqaku aphambili.

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