I-Raw Tianeptine i-hemisulfate i-monohydrate powder (i-1224690-84-9)

Oktobha 30, 2018

I-Tianeptine Sulfate, ekwabizwa ngokuba yiRaw Tianeptine hemisulfate monohydrate powder, yi …… ..


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum
Amandla: 1350kg / inyanga

I-Raw Tianeptine i-hemisulfate i-monohydrate powder (i-1224690-84-9) ividiyo

 

I-Raw Tianeptine i-hemisulfate i-monohydrate powder (i-1224690-84-9) Iinkcukacha

Igama lemveliso I-Raw Tianeptine i-hemisulfate i-monohydrate powder
Igama leKhemikhali Tianeptine hemisulfate monohydrate; 1224690-84-9; Heptanoic acid,
uhlobo Numama Stablon, Coaxil
Iqela leziyobisi AbaPhakathi kunye neMichiza elungileyo
Inani leCAS 1224690-84-9
InChIKey I-KVVMXNNJBVTOSX-UHFFFAOYSA-N
I molecular Fi-ormula C42H56Cl2N4O14S3
I molecular WSibhozo 1008.004 g / mol
IMasaisotopic Mass 1006.233 g / mol
Ukuxuba Point  1800 ℃
Ukubilisa Point 269.8 ° C kwi-760 mmHg
I-Biological Half-Life N / A
umbala Umoya oMhlophe
Sukufaneleka  I-Freetly soluble Emanzini kunye ne-methanol ne-dichloromethane
Sisibetho Tukushisa  Indawo eyomileyo
Aukuguquka I-tianeptine sodium ingasetyenziselwa kwi-Tricyclic isakhi kunye ne-psychostimulant

I-tianeptine sodium inomsebenzi wokulwa nesilonda kunye neepropati ezichasayo. Ukuxhatshazwa

 

I-Raw Tianeptine i-hemisulfate monohydrate (THM) powder (1224690-84-9)

I-Raw Tianeptine i-hemisulfate i-monohydrate powder, ebizwa nangokuthi iTianeptine Sulfate, yinguqu ephucukileyo yefayili ye-tianeptine yetyuwa ye-sodium. Akusiyo i-hygroscopic, kulula ukuyisebenzisa, ihla ilula, kwaye ihlala kabini ngokude. Inayo yonke inzuzo efana ne-Tianeptine Sodium, ifomu le-sulphate kuphela linomlinganiselo wobomi beeyure ze-5-6, ngoko lihlala kabini kwixesha le-soane. Ngenxa yoko, abaphandi baya kufuna ii-2-3 ngamaxesha e-sulfate ukuphumeza iziphumo ezifunwayo eziye zithandwa kwi-sodium. I-Sulfate nayo iphantsi kancinci kwisibini kunye ne-viscosity.

I-Tianeptine i-hemisulfate monohydrate ibalwa njengendlela yokukhetha i-serotonin yokuvuselela i-serotonake (SSRE) esetyenziselwa ukuphatha uxinzelelo. I-Tianeptine yaphuhliswa eFransi kwi-1960 kwaye isetyenziswe kuyo yonke indawo yokugqibela ye-2000s.

Kwakhona ngamanye amaxesha kusetyenziswa ukunyanga isifo sengqondo sesifo sengqondo okanye i-asthma. Kwizilingo ezinzima zichazwe ukuvelisa iziphumo zokuzonwabisa ezinjenge-opioid ezinjenge-sedation kunye nokuvuselela, ukuphucula ukukhuthazwa, kunye nokuzonwabisa xa kulawulwa.

Tianeptine hemisulfate monohydrate (THM) powder (1224690-84-9) Indlela yokusebenza

Enye yeendlela eziphambili zezenzo zeTianeptine hemisulfate monohydrate kukunyusa ukubanjwa kwe-serotonin (5-HT) kwingqondo nakwiiplatelets. Ngokungafaniyo nezixhobo ezininzi ze-tricyclic, i-Tianeptine ayibonakali inxulunyaniswa nokwehla kokusebenza kwengqondo okanye ukusebenza kwemoto. Kubonakala ngathi inemisebenzi kwinkqubo ye-glutamatergic, ethathelwa ingqalelo ukuba iyindlela yokulwa noxinzelelo.

Ngokwandisa ukuthatha i-serotonin, i-Tianeptine hemisulfate monohydrate ineendlela ezichaseneyo nee-SSRI zemveli. Izifundo zamva nje ziye zavavanya iimpembelelo zeTianeptine ngaphakathi kwesakhelo se-neuroplasticity hypothesis yoxinzelelo, apho inokuba nomsebenzi othile. Uphando lwamva nje lukwabonisa ukuba iTianeptine inokusebenzisana ne-adenosine A1 receptors.

Ngaphezulu, uphando olutsha lupapashwe kwi-2014 lubonisa ukuba iTianeptine inokusebenza njenge-m-opioid receptor (MOR) agonist. Abaphandi basebenzisa ii-radioligand ezizibophelelayo kunye nezilingo zokusebenza ezisetyenziselwa i-Tianeptine njenge-agonist esebenzayo ye-MOR. Kwakhona i-agonist epheleleyo ye-opioid kodwa ngobudlelwane obuphantsi kakhulu. I-tianeptine yayingenakusebenza kwiindawo ze-k-opioid receptor.

ukusebenzisa I-Tianeptine i-hemisulfate monohydrate (THM) powder (1224690-84-9)

▪ Ukudakumba

▪ Ukuxhalaba, ukuxinezeleka kunye neempawu ze-nootropic

▪ Ukusebenza kwengqondo, nokuphucula ubuchule bokufunda

▪ Intlungu yezihlunu

▪ ISIDIMA

Iphakanyiswe i-Tianeptine i-hemisulfate monohydrate (THM) powder (1224690-84-9) Isisombululo

I-Tianeptine hemisulfate monohydrate dosage i-25 mg kanye, okanye kabini ngemini. Nokuba uqala ngedosi esezantsi, kungcono ukuyikhawulela kwiintsuku ezi-2 okanye ezi-3 ngeveki ubuncinci iintsuku ezi-3 ukuya kwezi-4 phakathi.

I-Tianeptine hemisulfate monohydrate iza kwifomule okanye kwifom. Kuyacetyiswa ukuba uqale ngedosi esezantsi kwaye unyuke ngamanani amancinci de kufike idosi echanekileyo. Ukongeza, iidosi ezincinci zinciphisa ukubakho kwesiyobisi, ukurhoxa kakhulu kunye nokunyamezelana.

Imithamo ye-50-75 mg inokukhuthaza. I-Tianeptine hemisulfate monohydrate yedosi yokuzihlaziya ye> 100 mg inokubangela ukuba iTianeptine hemisulfate monohydrate ephezulu yokuziva.

Izinzuzo ze Tianeptine i-hemisulfate monohydrate (THM) powder (1224690-84-9)

I-Tianeptine hemisulfate monohydrate iphucula ubuchwephesha bengqondo kunye nokunciphisa uxinzelelo. I-Neuroplasticity kukukwazi kwengqondo ukuziqhelanisa nokutshintsha xa ufunda; ukufaka isandla ekusebenzeni ngcono kwengqondo kunye nokuphucula amandla okufunda.

Uphononongo lwezigulana ezingama-90 ezine-PTSD lubonise iziphumo ezincumisayo ngokusetyenziswa kweTianeptine hemisulfate monohydrate. Izifundo zikwabonakalisile ukuba ngonyango nge-tianeptine sulphate kunye nokuncitshiswa okubonakalayo kokuphazamiseka kwengqondo. I-Tianeptine hemisulfate monohydrate enikezelwe kwizigulana esele ikhulile ibonakalisile ekuphuculeni uxinzelelo lwe-neurocognitive function kunye nokuphuculwa kwemood.

♦ Izifundo zezilwanyana kunye noluntu ziye zenziwa ekwenzeni unyango lwe-Parkinson kunye ne-tianeptine hemisulfate monohydrate, ebonisa iziphumo ezithembisayo ekuphuculeni amanqaku empilo yengqondo.

Uphononongo lokuqala lwezonyango ezingama-68 ezine-ADHD zigqibe kwelokuba amanqaku aphuculweyo aphuculwe kakhulu kwaye i-Tianeptine hemisulfate monohydrate iluncedo ekwenzeni amandla okuqwalaselwa ngcono kunye nokwehla kweendlela zokuziphatha ezingasebenziyo.

♦ I-Tianeptine hemisulfate monohydrate ikwayi-analgesic esebenzayo (i-painkiller), kwanabantu abaphethwe ziintlungu ezingapheliyo. Yindlela esebenzayo yokufumana iimpawu ezinxulumene nemicimbi yezempilo yamathumbu ngokunjalo.

IZiko loNyango lwezeMpilo eCaracas liqhube uvavanyo lweeveki ezingama-52 olungenamkhethe lwabantwana abanesifuba. Izigulana ezilawulwa yi-Tianeptine hemisulfate monohydrate zibonise ukonyuka okukhulu ekusebenzeni kwemiphunga.

♦ Nangona uphando oluninzi lufunekayo, ukufundwa kwabasilisa be-237 abane-ED baqikelele ukuba i-tianeptine ingaba unyango osebenzayo.

♦ Iziphumo ze-Tianeptine ze-anxiolytic azichaphazeli kakubi umsebenzi we-acetylcholine okanye umsebenzi we-cardiovascular, okwenza i-tianeptine ibe yindlela enhle kakhulu kubantu abadala kunye nabanye