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I-NADH 2Na (606-68-8)

I-NADH luhlobo lwe-nicotinamide adenine dinucleotide (NAD) enzyme, indlela esebenzayo ye-coenzyme yecandelo kunye nevithamini B3 ……….


Isimo: KwiMveliso yoLuntu
I-Synthesized and Customized Available
Amandla: 1277kg / inyanga

inkcazelo

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) Iinkcukacha

Igama lemveliso I-Beta-Nikotinamide i-adenine dinucleotide disodium ityuwa (NADH 2Na)
Igama leKhemikhali I-NADH (ityuwa yedisodium); I-Disodium nicotinamide adenine dinucleotide; i-eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium salt; I-Nicotinamide adenine dinucleotide, ehlisiwe;
Inani leCAS 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
SMILE C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
I-Molecular Formula C21H27N7Na2O14P2
Isisindo somzimba 709.4
IMasaisotopic Mass 709.088661 g / mol
Indawo yokunyibilika 140-142 ℃
umbala Lubhelu
Sitempile yetanki 2-8 ℃
Umzimba I-H2O: 50 mg / mL, icace gca ecacileyo, etyheli
isicelo Unyango; ukutya kunye nezongezelelo zesondlo;

Yintoni i-Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)?

I-NADH luhlobo lwe-nicotinamide adenine dinucleotide (NAD) enzyme, indlela esebenzayo ye-coenzyme yecandelo kunye nevithamini B3. I-NADH (b-Nicotinamide adenine dinucleotide) Ityuwa ye-Dodium, encitshisiweyo, ekwabizwa ngokuba yiNicotinamide adenine dinucleotide, yi-coenzyme ekuphenduleni kwe-redox. Imisebenzi yayo njengokwenza umbane kwakhona onikezela nge-elektroni kwiinkqubo ze-catabolic kubandakanya i-glycolysis, β-oxidation kunye nomjikelo we-citric acid (umjikelezo weKrebs, umjikelo we-TCA). Ityuwa ye-NADH disodium nayo ithatha inxaxheba kwimicimbi yokubonisa iiseli, umzekelo njengesiqwengana seepolymerase zepoly (ADP-ribose) (PARPs) ngexesha lokuphendula komonakalo kwiDNA. Njengedawoti ye-disodium ye-NADH, isetyenziswa ekutyeni nakwizongezelelo zesondlo kunyango lwesifo sikaParkinson, isifo sokudinwa okungapheliyo, isifo seAlzheimer kunye nezifo zentliziyo.

Izibonelelo zeBeta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) izibonelelo

Njenge-coenzyme ye-oxidoreductases, i-NADH ityuwa ye-Dodium idlala indima ebalulekileyo kwimveliso yamandla omzimba.

-I-NADH ityuwa yesidudu inokukhokelela ekucacisweni okungcono kwengqondo, ukuphaphama, ukugxila kunye nememori. Inokonyusa i-acuity yengqondo kwaye inganyusa imo yeemvakalelo. Inganyusa amanqanaba amandla emzimbeni kunye nokuphucula imetabolism, amandla obuchopho kunye nokunyamezelela.

-Ukunceda abantu abanoxinzelelo lweklinikhi, uxinzelelo lwegazi oluphezulu okanye i-cholesterol ephezulu;

-Ukuphucula indlela yokusebenza kwezemidlalo;

-Ukulibaziseka kwinkqubo yokuguga kunye nokugcina ingqibelelo yeeseli zemithambo-luvo ukuxhasa inkqubo ye-nerve;

-Ukunyanga isifo sikaParkinson, ukuphucula ukusebenza kwengqondo yezigulana kwizifo zesifo sikaParkinson, ukunciphisa ukukhubazeka emzimbeni kunye neemfuno zamachiza;

-Ingcaphephe isifo sokudinwa okungapheliyo (CFS), isifo seAlzheimer kunye nesifo sentliziyo;

Khusela kwimiphumo emibi yeyeza likaGawulayo elibizwa ngokuba yi-zidovudine (AZT);

- Chasa imiphumo yotywala kwisibindi;

- Jet lag

I-Beta-Nikotinamide i-adenine dinucleotide disodium ityuwa (NADH 2Na) imiphumela:

Okwangoku, i-NADH disodium yetyuwa ibonakala ikhuselekile kubantu abaninzi xa isetyenziswe ngokufanelekileyo kunye nexesha elifutshane, ukuya kwiiveki ezili-12. Uninzi lwabantu alunazo naziphi na iziphumo ebezingalindelekanga xa kuthathwa isixa esinconywayo suku ngalunye, eyi-10 mg.

Nangona kunjalo, akukho datha yaneleyo malunga nokusetyenziswa kwe-NADH disodium yetyiwa ngexesha lokukhulelwa kunye nokuncancisa., Ke kufuneka bahlale kwicala elikhuselekileyo kwaye baphephe ukusetyenziswa.

Imbekiselo:

  • IBirkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) -indlela entsha yonyango kwisifo sikaParkinson. Thelekisa isicelo somlomo kunye nobuzali. I-Acta Neurol Scand Suppl 1993; 146: 32-5.
  • UBudavari S, umhleli. I-Merck Index. Ngomhla we-12. Isikhululo seWhitehouse, NJ: Merck & Co, Inc., ngo-1996.
  • I-Bushehri N, iJarrell ST, uLieberman S, et al. Ukuncitshiswa komlomo kwe-B-nicotinamide adenine dinucleotide (NADH) kuchaphazela uxinzelelo lwegazi, i-lipid peroxidation, kunye neprofayile ye-lipid kwiigundane zegazi (SHR). UGeriatr Nephrol Urol 1998; 8: 95-100.
  • I-Bushehri N, iJarrell ST, uLieberman S, et al. Ukuncitshiswa komlomo kwe-B-nicotinamide adenine dinucleotide (NADH) kuchaphazela uxinzelelo lwegazi, i-lipid peroxidation, kunye neprofayile ye-lipid kwiigundane zegazi (SHR). UGeriatr Nephrol Urol 1998; 8: 95-100.
  • UCastro-Marrero J, uCordero MD, uSegundo MJ, et al. Ngaba i-coenzyme Q10 yokudibanisa ngomlomo kunye ne-NADH eyongezayo iyaphucula ukukhathala kunye neparamitha yepharochemical kwi-Figue Flex syndrome? I-Antioxid Redox Signal 2015; 22 (8): 679-85.
  • UDizdar N, Kagedal B, Lindvall B. Unyango lwesifo sikaParkinson esine-NADH. I-Acta Neurol Scand 1994; 90: 345-7.

ISIQINISEKISO NESIBONELELO:

Le nto ithengiselwe uKwenziwa koPhando kuphela. Imigaqo yokuthengisa Faka isicelo. Ayisetyenziselwa uBuntu, okanye oNyango, iZilwanyana, okanye abaNtu.


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I-NADH 2Na (606-68-8) ividiyo

IAAA

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