I-Pyrroloquinoline quinone disodium salt (122628-50-6)

Matshi 16, 2020
SKU: 65-19-0-2

I-PQQ luhlobo olutsha lweevithamini ezinyibilikiswa ngamanzi, yafunyanwa okokuqala njenge-cofactor ye …….


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum

Ividiyo ye-Pyrroloquinoline quinone disodium salt (122628-50-6) ividiyo

I-Pyrroloquinoline quinone disodium salt (122628-50-6) Iinkcukacha

Igama lemveliso I-Pyrroloquinoline quinone disodium salt (122628-50-6)
Igama leKhemikhali I-Pyrroloquinoline quinone sodium ityuwa; disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo (2,3-f) quinoline-2,7,9-tricarboxylat; PQQ, Pyrrolo-quinoline-quinone disodium ityiwa; sodiuM 9-carboxy-4,5 -dioxo-4,5-dihydro-1H-pyrrolo [2,3-f] quinoline-2,7-dicarboxylate; PQQ disodium
Inani leCAS 122628-50-6
InChIKey I-UFVBOGYDCJNLPM-UHFFFAOYSA-L
SMILE C1=C(C2=C(C(=O)C(=O)C3=C2NC(=C3)C(=O)O)N=C1C(=O)[O-])C(=O)[O-].[Na+].[Na+]
I-Molecular Formula C14H4N2Na2O8
Isisindo somzimba 374.17
IMasaisotopic Mass 373.976304 g / mol
Indawo yokunyibilika > 300 ℃ (ibunjiwe ngexesha lokuhamba)
umbala Ubomvu o-orenji ukuba abe ngophawu oluBomvu lweFine brown
Indawo yokugcina 2-8 ° C
Umzimba I-Soluble emanzini
isicelo IProdroloquinoline quinone (PQQ) ityuwa yesidiliya icetyiswa ukusetyenziswa ngenxa yexabiso lesondlo e-United States (e-US) ekudleni, njengamandla, ezemidlalo kunye neziselo ze-isotonic; iziselo ezingasuswanga kubisi; amanzi (asebhotileni, aphuculweyo, aqinisiweyo); iziphuzo ezisuselwe kubisi; imitya yokutya okuziinkozo kunye negranola; kunye namandla, ukutshintshwa kwesidlo, kunye nemivalo enqatyisiweyo.

Yintoni iPyrroloquinoline quinone disodium salt (ityuwa yePodium yeDPQ)?

I-PQQ luhlobo olutsha lweevithamini ezinyibilikiswa ngamanzi, yaqala ukufunyanwa njenge-cofactor yokuphendula kwe-enzyme kwiibacteria, apho isebenza khona umsebenzi ofanayo weevithamini ze-B ebantwini. Yinto esekwe yi-oxidoreductase, ekhoyo kwezinye izinto ezincinci, izityalo kunye nezicubu zezilwanyana, engabandakanywanga kuphela kukhuselo lwe-oxidation yokuphendula komzimba, kodwa ikwanomsebenzi okhethekileyo webhayoloji kunye nomsebenzi womzimba. Umkhondo we-PQQ unokuphucula imetabolism yezicubu zebhayoloji kunye nokukhula komsebenzi, kubaluleke kakhulu.

Wenza njani uPyrUmsebenzi we-roloquinoline quinone disodium yetyiwa?

I-Pyrroloquinoline quinone disodium yetyuwa inokubandakanya isenzo ngqo kwi-enzymes ephambili ebandakanyekayo kumandla okuvelisa amandla kwiiseli zethu - i-mitochondria, theapy iphucula imveliso yamandla. I-Pyrroloquinoline quinone disodium ityuwa Ukongeza kwisiphumo esinamandla se-antioxidant, ikwakhusela nxamnye nomonakalo we-mitochondrial. Ayikhuseli nje i-mitochondria koxinzelelo lwe-oxidative, ikwakhuthaza isizukulwane esizimeleyo se-mitochondria entsha ngaphakathi kweeseli zokuguga.

Izibonelelo zePyrroloquinoline quinone disodium yetyiwa

I-Pyrroloquinoline quinone disodium ityuwa yinto yendalo esele ikhona kwiiseli zethu, inezibonelelo ezilungileyo ebantwini:

-Nceda ukuphucula ukungasebenzi komzimba kunye nokusebenza kwengqondo ephezulu;

-Khusela kunye nokunyanga ukonakala kwesibindi;

-Ucutha ukonakaliswa simahla komzimba womntu;

-Ukulawula izifo ezahlukeneyo ze-neurological;

-Ukunciphisa ukuthanda ukungena kwama-amino acid;

-Khusela kunye nokunyanga isifo se-alzheimer;

-Iiseli ezisebenzayo ze-NK, zongeza umsebenzi we-antitumor;

-Umgangatho wokulala ophuculweyo kunye nexesha kunye nezinye iimetri ezisekondari ukuphucula ukulala;

-Ukunyusa izinto ezikhutshelweyo ezenza ukuba kusebenze iindlela ze-antioxidant;

-Ukhuthaza ukwakheka kwe-mitochondria entsha kunye nokunyusa ukuveliswa kwamandla eselula.

Ukusetyenziswa kwe IPyrroloquinoline quinone disodium ityuwa

I-Pyrroloquinoline quinone disodium ityuwa ityuwa ye-disodium ye-Pyrroloquinoline quinone, ukusebenza kwayo kuyafana nePyrroloquinoline quinone.

Kuphononongo luka-2009 olupapashwe kwijenali yezonyango yokuTya, iPyrroloquinoline Quinone ibonakalisiwe ukuba inesakhono sokukhusela. Isetyenziselwa ukukhusela ukwehla kwengqondo (ukulahleka kwenkumbulo, ubunzima bokufunda, njl. Njl.) Ngenxa yobudala, ukubetha okanye ukuphazamiseka kwemithambo-luvo, kunye nokukhuseleka kwimicimbi yentliziyo kunye nesehlo se-ischemic. Iziphumo ezifanayo ziye zaxelwa kuphando lokulandela luka-2011 apho iPyrroloquinoline Quinone nayo yanikwa ngokuthe ngqo njengesongezelelo sokutya, ezinje ngobisi olususela kwisiselo sobisi.

Imbekiselo:

[1] Nakano M, Takahashi H, Koura S, Chung C, Tafazoli S, Roberts A. Acute kunye ne-subchronic toxicity yezifundo ze-pyrroloquinoline quinone (PQQ) ye-disodium yetyiwa (BioPQQ ™) kwiigundane. Ukulawula iToolol Pharmacol. Ngo-2014 Oct; 70 (1): 107-21. doi: 10.1016 / j.yrtph.2014.06.024. Epub 2014 Jul 1. PMID: 24995591.

[2] Itoh Y, Hine K, Miura H, Uetake T, Nakano M, Takemura N, Sakatani K. Isiphumo se-Antioxidant Supplement Pyrroloquinoline Quinone Disodium salt (BioPQQ ™) kwimisebenzi yokuqonda. I-Adv Exped Bi Biol. Ngo-2016; 876: 319-325. doi: 10.1007 / 978-1-4939-3023-4_40. I-PMID: 26782228.

[3] Nakano M, Kawasaki Y, Suzuki N, Takara T. Iziphumo zePyrroloquinoline Quinone Disodium salt Intake kumaNqanaba eSerum Cholesterol aBadala baseJapan abanempilo. J Nutr Sci Vitaminol (Tokyo). Ngo-2015; 61 (3): 233-40. doi: 10.3177 / jnsv.61.233. I-PMID: 26226960.

[4] Rucker R, Chowanadisai W, Nakano M. Ukubaluleka komzimba ngokubaluleka kwe-pyrroloquinoline quinone. Enye into uMfu Rev (ngo-2009)

[5] UNoji N, et al. Indlela elula kunye neyobuthathaka yokuhlalutya i-pyrroloquinoline quinone (PQQ) kwizidlo ezahlukeneyo kusetyenziswa amanzi chromatography / electrospray-ionization tandem mass spectrometry. J Agric Ukutya kwiChemicals (2007)