I-Powostilbene powder emfutshane (537-42-8)

Disemba 28, 2018
SKU: 537-42-8
5.00 ngaphandle kwe 5 ngenxa ye 1 ireyithingi abathengi

I-Pterostilbene powder yi-antioxidant ekho ikakhulukazi ikhona kwi-blueberries, iidiya neenkuni ze-sandalwood ezibomvu. Pterostilbene .......


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum
Amandla: 1180kg / inyanga

I-Powostilbene powder (537-42-8)

I-Powostilbene powder emfutshane (537-42-8)

I-Pterostilbene powder e-Raw-stilbenoid eyenziwe ngokwemvelo ehambelana ne-resveratrol, ene-antioxidant, i-anti-inflammatory, pro-apoptotic, i-antineoplastic kunye ne-cytoprotective. Phezu kokulawulwa, i-Raw Pterostilbene powder inomsebenzi wokulwa ne-oxidant ngokurhawula iintlobo ze-oksijeni ezisebenzayo (i-ROS), oko kukuthintela uxinzelelo lwe-oxidative kunye nomonakalo we-ROS. Inokuphinda isebenze i-nrythroid ye-2 ehambisana ne-2 (Nrf2) -yindlela edibeneyo kwaye inyuse imbonakalo yee-enzyme ezahlukahlukeneyo ezinjenge-antioxidant, njenge-superoxide dismutase (SOD). Ukongeza, i-Raw Pterostilbene powder iyakwazi ukuvimbela ukuvuvukala ngokunciphisa imbonakalo yabameli abavuthayo, njenge-interleukin (IL) 1beta, i-tumor necrosis i-alpha (TNF-a), i-nitric oxide synthase (iNOS), i-cyclooxygenase (COX) , kunye ne-nyukliya factor kappa B (NF-kB). Kwakhona kuvimbela okanye kuvimbela ukusetyenziswa kweendlela ezininzi zokungena ezibandakanyekayo kwi-carcinogenesis, kunye nokwandisa ukubonakalisa iintlobo ezahlukeneyo zengcinezelo zegciwane ngexesha lokunciphisa intlungu ethile ekukhuthazeni izakhi zofuzo. Ikwazisa ngqo iipoptosis kwiiseli zesisu.

I-Powostilbene powder (Rax-537-42)uqobo

Igama lemveliso Powostilbene powder
Igama leKhemikhali Powostilbene powder;

4-(3,5-Dimethoxystyryl)phenol; (E)-4-(3,5-dimethoxystyryl)phenol; 3′,5′-Dimethoxy-4-stilbenol

uhlobo Numama Akukho datha ekhoyo
Iqela leziyobisi Akukho datha ekhoyo
Inani leCAS 537-42-8
InChIKey VLEUZFDZJKSGMX-ONEGZZNKSA-N
I molecular Fi-ormula C16H16O3
I molecular WSibhozo 256.301 g / mol
IMasaisotopic Mass 256.11 g / mol
IMisa eyiyo 256.11 g / mol
SMILES CC1=C(OC2=NC3=C(CCCC3)C(=C12)NC(=O)CN4CCCC4=O)C
I-Biological Half-Life Akukho datha ekhoyo
umbala Powder
Sukufaneleka Akukho datha ekhoyo
Sisibetho Tukushisa Gcina kwiqondo lokushisa
Aukuguquka I-stilbenoid eyenziwa ngokwemvelo ngokumalunga ne-resveratrol

I powttilbene powder (537-42-8) Inkcazo

I-Pterostilbene yi-methylated stilbene i-molecule ene-structural similarity to resveratrol, umahluko nje kuphela ngamaqela e-methoxy kwi-molecule ye-pterostilbene ebeka amaqela e-hydroxy kwi-molecule ye-resveratrol. Ngelixa ezininzi zezenzo zale mibini zifaniswa, i-pterostilbene ibonakala ixutywa kakuhle emva kokungcinywa komlomo kwaye ingaba yintsholongwane enamandla kunye ne-antiticancer molecule.

Uphando olulodwa luye lwavavanya ipterostilbene powder kubantu. Ifumene ukwanda kwe-LDL-cholesterol kunye nomgangatho wokufikelela kumazinga angaphantsi kwe-HDL kubantu abanezinga eliphezulu le-cholesterol ezithatha i-100 okanye i-250 mg ngosuku. Kwakungacaca ukuba i-dose ephantsi iholele ekunciphiseni uxinzelelo lwegazi, kodwa ukunciphisa iqela elithatha umthamo ophezulu kunamandla.

I-Pterostilbene powder (537-42-8) Indlela yokuSebenza

I-Pterostilbene ilwa nokuxinwa kwe-oxidative ngokubalinganisa i-enzymes e-antioxidant. Yandisa i-superoxide dismutase i-1 (i-SOD1) kunye ne-peroxiredoxin-i-4 (i-PRDX4), ebophezela kwiintlobo ze-oksijeni ezisebenzayo. Abaphandi baye babona oku kusebenza kumaseli esiso lomntu, bacetyisa ukuba i-pterostilbene inokukhusela kumonakalo ochaphazelekayo. Ngaphandle, i-Pterostilbene ibuye isebenzise indlela yokubonakalisa i-SIRT1 ekhusela umonakalo wamaselula. Le ndlela iyakwandisa ukubonakalisa kwe-P53, iprotheni ekhusela i-DNA kwaye ikhusela utshintsho olubangelwa ngumhlaza.

Nangona i-SIRT1 inokukhusela ngokuchasene nokunye ukuguqulwa kunye nomonakalo owenzekayo njengoko sikhula. Nangona kunjalo, i-pterostilbene ayikho ipilisi yamatshini ngokuguga.

Izifundo ezininzi ziye zabonisa ukuba i-pterostilbene iyancipha ukuvuvukala okulawulwa yi-tumor necrosis-alpha-alpha (TNF-alpha). Uxinzelelo oluxhasiweyo lubangela ukuvuvukala; i-pterostilbene ingavimba i-TNF-alpha kunye ne-interleukin-1b (i-IL-1b) ngokunciphisa iintlobo ze-oksijeni ezisebenzayo.

I-Pterostilbene iphinde ivimbe uxinzelelo phakathi kwendawo yamashishini eselula ebizwa ngokuba yi-endoplasmic reticulum, okanye i-ER. Kwisifundo esithile, xa iiseli ezivela kumbindi wegazi zibonakaliswe kwi-pterostilbene, i-ER yabo ayizange iphendule kwiimpawu ezivuthayo, kwaye azizange zitshathwe.

I-Pterostilbene inomlinganiselo omkhulu weendlela zokulwa nomhlaza. Inokukhusela iiseli ezinempilo kwaye yonakalise ngokukhethekileyo iiseli zomhlaza. Kwi-glioma (ingqondo okanye umhlaza womgudu), i-pterostilbene yehle i-Bcl-2 kunye ne-Bax eyandisiweyo; olu tshintsho lwandisa iseli "ukuzibulala" kwaye lubangela iiseli ze-glioma ukuba zife.

I-Pterostilbene ibonakala ijolise ngokukhethekileyo kwingingqi ye-hippocampus kwingqondo. Kukho, kwandisa ingqondo ye-neurotrophic factor (BDNF), iprotein kinases (activated protein kinase) ye-mitogen, kunye ne-cAMP impendulo ebopha iprotheni (CREB). Ezi ntathu zeprotheni zisiza i-neurons ukuba ikhule, iphindise, iphinde iphendule kwiindawo ezikuyo. I-SNRI i-anti-pressressants often often target these paths. Kwakhona kwi-hippocampus, i-pterostilbene yandisa iprotheni ebizwa ngokuba yi-Nrf2, leyo eyenza ukuba ikhulise iiprotheni ezixhatshazwayo.

I-monoamine oxidases, ii-MAO, ziyi-enzymes eziphula i-neurotransmitters kwingqondo. Enye yezi-enzymes, i-MAO-B, ikhethile i-dopamine ngokukhethekileyo; ngenxa yoko, iziyobisi ezivimba ii-MAO-B ukwandisa i-dopamine kwingqondo. Ngokutsho kokufumanisa kwangoko, i-pterostilbene inhibits u-MAO-B umsebenzi kwaye, ngoko ke, ukwandisa i-dopamine.

I-Pterostilbene powder inokuthintela isifo se-Alzheimer ngokukhusela ingqondo kwi-beta-amyloid (Aβ). Indlela echanekileyo ayiyaziwayo, kodwa ibonakala iquka i-PI3K kunye ne-akt, iiprotheni ezimbini ezixhasa imemori, ukufunda kunye ne-neuron ukukhula.

ukusebenzisa I-Pterostilbene powder (537-42-8)

  • Isifo se-Alzheimer
  • Atherosclerosis
  • Diabetes
  • Igazi elonyukayo
  • Cholesterol ephezulu
  • Ukuxhathisa kwe-insulin

Iphakanyiswe iPterostilbene powder (537-42-8) Isisombululo

Kubantu, amanani ukuya kwi-250 mg ngosuku ayabonwa njengokhuselekile. Amanani aphakamileyo afana nalawa abonakalisiwe ukunciphisa uxinzelelo lwegazi nokukhuthaza ukulahleka kwesisindo. Amanqanaba e-LDL e-cholesterol akhula ngokukodwa, kodwa le mpembelelo yayinganyelwanga ngokupheleleyo kunye nokudibaniswa kweminye yembewu yamagilebhisi.

Kwizilwanyana, amanani amaninzi aphantsi ayenemiphumo engqondweni. Phakathi kwe-1 kunye ne-2 mg ngekg weesisindo somzimba ngosuku liyanciphisa ukuxhalaba kwiigundane. Ukusebenzisa ukulinganisa okulinganayo kwenzalo phakathi kwamagundane nabantu, i-dose yokuqala (kwi-mg) yomntu yayiza kuba isisindo sayo kwi-kg ehlukaniswe yi-12.3. E sebenza ku:

4.6 mg / usuku lomntu we-125 lb

5.5 mg / usuku lomntu we-150 lb

6.5 mg / usuku lomntu we-175 lb

7.3 mg / usuku lomntu we-200 lb

Ukuba uthatha ipterostilbene powder ngenxa yeenzuzo zayo zokuqonda, unokufisa ukuqala ngeqondo eliphantsi kakhulu. Nangona kunjalo, iziphumo ezinjalo eziphantsi kwezonyango ziye zabonwa kuphela kwiimicebe ngoku, kwaye abantu banokuyonwabela kakhulu inzuzo engqondweni kunye namaqondo aphezulu.

Iinzuzo zePterostilbene powder (537-42-8)

I-Pterostilbene powder yi-antioxidant ekhoyo ngokuyinhloko, nayo ine-chemopreventive, antiinflammatory, antidiabetic, antidyslipidemic, antiatherosclerotic kunye neuroprotective effects. Ngaphandle koko, kunamathuba athile apha ngezantsi:

  • Unceda ukulwa nomhlaza
  • Ukuphucula ukuqonda kunye nokuvimbela ukufa kwesisele kwiingqondo
  • Iyanciphisa i-Blood Sugar
  • Iyanciphisa ukuvuvukala
  • Ukhusela iSibindi
  • Unokukhusela Intliziyo
  • Kwangathi Unokuxhasa Ukulahlekelwa Kwisisindo
  • Ukhusela Amehlo
  • Kwangathi Inganda iMpilo
  • Ukunciphisa uxinzelelo lwegazi

ISIQINISEKISO NESIBONELELO:

Le nto ithengiselwe uKwenziwa koPhando kuphela. Imigaqo yokuthengisa Faka isicelo. Ayisetyenziselwa uBuntu, okanye oNyango, iZilwanyana, okanye abaNtu.