I-Lactoferrin (146897-68-9)

Matshi 15, 2020

ILactoferrin (LF), ekwabizwa ngokuba yi-lactotransferrin (LTF), yiglycoprotein emelwe ngokubanzi kulwelo oluyimfihlo oluquka ……

 


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum

 

I-Lactoferrin (146897-68-9) ividiyo

I-Lactoferrin powder Suqobo

Igama lemveliso I-Lactoferrin
Igama leKhemikhali I-lactotransferrin (LTF)
uhlobo Numama N / A
Iqela leziyobisi N / A
Inani leCAS 146897-68-9
InChIKey N / A
I molecular Fi-ormula C141H224N46O29S3
I molecular WSibhozo I-87 kDa
IMasaisotopic Mass N / A
Indawo yokubilisa  N / A
Fukuhlaziywa kwakhona Point N / A
I-Biological Half-Life N / A
umbala pink
Sukufaneleka  I-H2O: 1 mg / mL
Sisibetho Tukushisa  2-8 ° C
Aukuguquka N / A

 

Yintoni i I-Lactoferrin?

I-Lactoferrin (LF), ekwabizwa ngokuba yi lactotransferrin (LTF), yi-glycoprotein emelwe ngokubanzi kwiindawo ezahlukeneyo zokugcina amanzi kubandakanya ubisi. Le CRM yobude obugcweleyo ilungile njengokuqala kwezinto zokusetyenziswa kwe-calibrators okanye kulawulo lweentlobo ngeentlobo zovavanyo lwe-LC-MS / MS kubandakanya nokuvavanywa kwe-allergen, uvavanyo lwefomyula yabantwana, ukutya okanye ukutya okunesondlo kunye novavanyo lokuqonda

I-Colostrum, ubisi lokuqala oluveliswe emva kokuba umntwana luzelwe, luqukethe amanqanaba aphezulu e-lactoferrin, malunga nesixhenxe isixa esifumaneka kubisi oluveliswe kamva. I-lactoferrin ikwafumaneka kulwelo emehlweni, impumlo, indlela yokuphefumla, amathumbu, nakwezinye iindawo. Abantu basebenzisa i-lactoferrin njengeyeza.

I-Lactoferrin isetyenziselwa ukunyanga izilonda zesisu kunye namathumbu, iswekile, kunye nehepatitis C. Ikwasetyenziswa njenge-antioxidant kunye nokukhusela kwizifo ezibangelwa yintsholongwane kunye nentsholongwane. Olunye usetyenziso lubandakanya ukuvuselela amajoni omzimba, ukuthintela ukonakaliswa kwezicubu ezinxulumene nokwaluphala, ukukhuthaza iibacteria ezinempilo yamathumbu, ukuthintela umhlaza, kunye nokulawula indlela umzimba oqhuba ngayo isinyithi.

Abanye abaphandi bacebisa ukuba i-lactoferrin inokudlala indima ekusombululeni iingxaki zempilo zehlabathi njengokusilela kwentsimbi kunye nesifo seswekile esikhulu.

Kwimo yezolimo, i-lactoferrin isetyenziselwa ukubulala iintsholongwane ngexesha lokucocwa kwenyama.

I-Lactoferrin yinxalenye yenkqubo yomzimba yokuzikhusela kwaye ine-antimicrobial activity. Ukongeza kwimisebenzi ephambili yokudibanisa kunye nokuhambisa isinyithi, i-Lactoferrin ikwanemisebenzi kunye neempawu zentsimbi ye-antibacterial, i-antivirus, ukumelana ne-parasites, i-catalysis, ukuthintela umhlaza kunye nokulwa umhlaza, i-allergies kunye nokukhuselwa kwemitha. Abanye abantu bathatha izongezo ze-lactoferrin ukufumana izibonelelo ze-antioxidant kunye ne-anti-inflammatory.

Izibonelelo zeLactoferrin

Iziphumo zokuchasana nokuvuvukala

Nangona umatshini ngqo ungakhange usekwe okwangoku, i-lactoferrin yinto eyaziwayo ye-anti-insulin ebantwini.

I-lactoferrin kwi-amniotic fluid yinto ebalulekileyo yokunciphisa ukuvuvukala kwesibeleko kubafazi abakhulelweyo ngokunciphisa amanqanaba e-IL-6 kunye nokunciphisa usulelo olubangela ukuvuvukala.

Inezinto ezinxamnye nokuvuvukala xa zidibana nenkqubo yomzimba yokuzikhusela kwi-Epstein-Barr virus, ukunciphisa ukuvuvukala ngokuthintela ukuvulwa kwe-TLR2 kunye ne-TLR9 kwi-DNA yentsholongwane.

Izinto zeAnbacterial

I-Lactoferrin inceda ukumisa umsebenzi weentsholongwane. Uninzi lweebhakteriya zidinga i-iron ukuze isebenze, kwaye i-lactoferrin inokuyekisa iibhaktheriya ekubeni ithathe i-iron emzimbeni womntu.

Ukongeza koku, inokuthi ivimbe i-carbohydrate metabolism metabolism, ibeke iindonga zeseli yazo, okanye isebenzisane nee-lysozymes zobisi ukuyeka ii-bacteria.

Iindima kuphuhliso lweentsana / ukukhula komntwana

Iintsana zifuna i-lactoferrin ukuphuhlisa kunye nokuhambelana nenkqubo yamathumbu. Linoxanduva lokwahlula iiseli zamathumbu amancinci e-epithelial, ezichaphazela ubuncinci bamathumbu, ubude, kunye nenkcazo ye-enzyme.

Kwizibeleko zabantu, i-lactoferrin isebenza njengomlawuli wokukhula kwethambo kwizigaba zokuqala zophuhliso lwamathambo omntu.

I-Lactoferrin ikhuthaza ukukhula kweethishu ze-cartilaginous kumanqanaba ohlukeneyo okukhula kwesibeleko ngokuvuselela i-osteocytes kunye ne-osteoblasts.

Kwiintsana zomntu, i-Lactoferrin ikhuthaza ukumiselwa kwesinyithi kunye nokuphuhliswa komda webrashi, okuvumela ukukhula okunempilo kunye nokukhula kwesisu ngaphambi kokuzalwa.

Amanqanaba aphezulu e-Lactoferrin esibelekweni athintela usulelo kunye nokuqhekeka kolusu lwe-fetus ngelixa lonyusa ukubulaleka.

 

Isebenza njani iLactoferrin?

I-Lactoferrin inceda ukulawula ukumiliselwa kwesinyithi emathunjini kunye nokuhanjiswa kwensimbi kwizisele.

Ikwabonakala ikhusela ngokuchasene nokusulelwa yintsholongwane, ngokunokuthi kuthintele ukukhula kweebacteria ngokuzincekisa izakha mzimba okanye ngokubulala iintsholongwane ngokutshabalalisa iindonga zesisele sazo. I-lactoferrin equlethwe kubisi lukamama ibonakaliswa ngokuncedisa ukukhusela abantwana abancanciswe kwisifo seentsholongwane.

Ukongeza kusulelo lwebhaktiriya, i-lactoferrin ibonakala isebenza ngokuchasene nosulelo olubangelwa ziintsholongwane ezithile kunye nesikhunta.

I-Lactoferrin ikwabonakala ngathi iyabandakanyeka kumgaqo wokusebenza komongo wamathambo (myelopoiesis), kwaye kubonakala ngathi iyakwazi ukomeleza inkqubo yokhuseleko lomzimba (immune).

 

Iziphumo ebezingalindelekanga zeLactoferrin

I-Lactoferrin powder ikhuselekile kwimali esetyenziswe ekutyeni. Ukutya izixa eziphezulu ze-lactoferrin kubisi lwenkomo kunokuba kukhuselekile ukuya kuthi ga kunyaka. I-lactoferrin yomntu eyenziwe ngerayisi eyenziwe ngokukodwa ibonakala ikhuselekile ukuya kwiintsuku ezili-14. I-Lactoferrin inokubangela urhudo. Kwiidosi eziphezulu kakhulu, irhashalala, ukungabinamdla wokutya, ukudinwa, ukugodola kunye nokuqhinwa kuye kwaxelwa.

 

I-Lactoferrin powder setyenziso kunye nesicelo

I-MILK EFANELEKILEYO kunye ne-LACTOFERRIN

Kwiintsana ezisandula ukuzalwa ubunzima obunobunzima obutsha, ubisi lweentsana olutyebileyo nge-lactoferrin (enayo okanye ngaphandle kweeprotheyikhi) inciphisa umngcipheko wokulibaziseka kokuqala kwe-septicemia (intsholongwane okanye ukhunta).

Uhlalutyo olunzulu lweziphumo lubonise ukuba i-bovine lactoferrin inciphisile usulelo kunokuthintela isikhunta ukuba singasasazeki. Oku kuthetha ukuba i-lactoferrin iyakwazi ukuthintela usuleleko lokungunda lube sisifo se-systemic.

I-Bovine lactoferrin inokuwunqanda umqobo wegazi-ngengqondo kusetyenziswa ii-receptors ezithile, kwaye iphucule i-neuroprotection, i-neurodevelopment kunye namandla okufunda kwizilwanyana ezanyisayo.

 

isingqiniso:

  • U-Barrington K et al, Isilingo se-Lacuna: ulingo oluva kabini nolulawulwa ngokungekho mthethweni lilungelo lokufakelwa kwe-lactoferrin elusaneni olungekazalwa, uJ Perinatol. Ngo-2016 Aug; 36 (8): 666-9.
  • I-Lauterbach R et al., Lactoferrin -iglycoprotein yamandla amakhulu onyango, ixesha le-Dev Med. Ngo-2016 ngoMatshi-Juni; 20 (2): 118-25.
  • I-Nbr1 elawulwa yi-autophagy e-Lactoferrin-induced osteoblastic umahluko. UZhang Y, Zhang ZN, Li Li, Zhao LJ, Xue Y, Wu HJ, Hou JM. I-Biosci Biotechnol Biochem. 2020 Mar
  • Isiphumo seDosi yeBovine Lactoferrin yoLungelelwaniso kwi-Iron Metabolism yeAnants Infants. I-Chen K, Zhang G, Chen H, Cao Y, Dong X, Li H, Liu C. J Nutr Sci Vitaminol (Tokyo). 2020
  • I-Lactoferrin: Umdlali oBalulekileyo kuKhuselo lweSixeko seNeat. UTelang S et al. Izondlo. (2018)
  • Indima yeLactoferrin kwiiNeonates kunye neentsana: uhlaziyo. UManzoni P et al. NdinguJ Perinatol. (2018)
  • Ukufakwa kwe-lactoferrin yokufakelwa kokuthintela i-sepsis kunye necrotizing ye-enterocolitis kwiintsana zangaphambi kwexesha. UPammi M et al. I-Cochrane Database Database Syst Rev (2017)
  • Zithini izibonelelo zeLactoferrin eziBonelela abantu abadala kunye neeintsana?