I-Meclofenoxate (Centrophenoxine) (51-68-3)

Matshi 11, 2020
SKU: 541-15-1
5.00 ngaphandle kwe 5 ngenxa ye 1 ireyithingi abathengi

IMeclofenoxate (Centrophenoxine), ethengiswe phantsi kwegama lophawu lukaLucidril, yenye yezona zindala kakhulu kwaye ifundwe kakhulu ………


Isimo: KwiMveliso yoLuntu
Iyunithi: 25kg / Drum

I-Meclofenoxate (Centrophenoxine) (51-68-3) ividiyo

I-Meclofenoxate (Centrophenoxine) ipoda Suqobo

Igama lemveliso I-Meclofenoxate (Centrophenoxine) (51-68-3)
Igama leKhemikhali Clophenoxate;
I-Meclophenoxate;
Clofenoxin;
I-Proseryl;
2- (dimethylamino) ethyl 2- (4-chlorophenoxy) acetate
uhlobo Numama N / A
Iqela leziyobisi Ii-anti-Allergic Agents, ii-Antineoplastic Agents, i-Antiparasitic Age
Inani leCAS 51-68-3
InChIKey XZTYGFHCIAKPGJ-UHFFFAOYSA-N
I molecular Fi-ormula C12H16ClNO3
I molecular WSibhozo 257.71 g / mol
IMasaisotopic Mass 257.081871 g / mol
Indawo yokubilisa 345.941 ° C kwi-760 mmHg
Fukuhlaziywa kwakhona Point N / A
I-Biological Half-Life iiyure 2-4
umbala mhlophe
Sukufaneleka Ukunyibilika kwamanzi: 2.9 mg / mL
Sisibetho Tukushisa -20 ° C
Aukuguquka I-Centrophenoxine powder isebenzise iziyobisi ze-nootropics kunye nezongezo zokutya.

Ukujonga ngokubanzi iMeclofenoxate (Centrophenoxine)

IMeclofenoxate (Centrophenoxine), ethengiswe phantsi kwegama lophawu lukaLucidril, yenye yezona zokuqala kunye nezifundo ezixhaphakileyo zezifundo ze-nootropics okanye iziyobisi ezibizwa ngokuba "zi-smart". Yaziwa ngokuba yi-nootropic eyaziwayo kwaye ihlonitshwayo esele izibonakalise ngaphezulu kweminyaka engamashumi amahlanu yokusetyenziswa kunye novavanyo oluqinileyo lweklinikhi.

Kwaqala ukuphuhliswa ngo-1959 ngoososayensi kwiZiko loPhando lweSayensi yaseFransi njengonyango lwe-Alzheimer, ukuhamba kwegazi okungalunganga, ‍ kunye nokwehla kwengqondo okuhambelana nobudala, eli chiza lisetyenziswa ngokubanzi kunyango lweengxaki zobuchopho ezinxulumene nobudala, njenge-Alzheimer's kunye ne-dementia. Isetyenziswe ngabantu abaphilayo ukuphucula inkumbulo kunye nokuqonda kwengqondo kunye nokuphucula impilo yengqondo iphela.

Uphando lubonakalise i-centrophenoxine powder ukuba ibe ngumthombo onamandla wokukhumbula kunye ne-anti-ukuguga.

E-Yurophu, imiselwe unyango lokulahleka kwenkumbulo okunxulumene nobudala, kodwa ifumaneka ngaphezulu kwekhawuntari njengesixhobo sokutya e-US nase-Canada, apho isetyenziswa rhoqo kwizakhiwo zayo zokwazisa.

Yintoni iMeclofenoxate (Centrophenoxine)?

ICentrophenoxine isetyenzisiwe njengendawo yokutya eyongezayo malunga nokukwazi ukukhulisa amandla okukhumbula.

ICentrophenoxine yindibaniselwano yeekhemikhali ezimbini:

I-Dimethyl-aminoethanol (DMAE), eyinto yendalo efumaneka kokunye ukutya (intlanzi, intlanzi yolwandle) kunye nezixa ezincinci kwingqondo. Ngumthombo we-choline kwaye uneziphumo ezivuselela ingqondo.

I-Parachlorphenoxyacetic acid (pCPA), inguqulelo yokwenziwa kweehormon zokukhula kwezityalo ezibizwa ngokuba yi "auxins".

I-DMAE lelona candelo lisebenzayo kwesi siyobisi. I-DMAE ayiweli kakuhle kwisithintelo segazi-ngengqondo. Nangona kunjalo, ngaphakathi kwe-centrophenoxine, inokuhamba ngokuthintela igazi-ingqondo kwaye ingene ngengqondo ngokufanelekileyo

Nje ukuba ifakwe emzimbeni, isahlulo se-centrophenoxine sihlehlela kwi-DMAE kunye ne-pCPA kwisibindi. I-DMAE iguqulwa ibe yi-choline, ngelixa i-centrophenoxine eseleyo ijikeleza umzimba wonke.

Izibonelelo zeMeclofenoxate (Centrophenoxine)

ICentrophenoxine inokunceda ekulweni umhlaza.

ICentrophenoxine inokunceda iimpawu zedyskinesia ekuhambeni kwexesha.

I-Centrophenoxine iphucula inkumbulo kunye nokufunda, inokuphucula inkumbulo kwizigulana ezinesifo sengqondo esixhalabisayo.

I-Centrophenoxine ibonakalisiwe ukuphucula ukwakheka, ukugcinwa, kunye nokubuyiswa kweenkumbulo. Ukwenziwa kwememori kuphuculwe xa sinamanqanaba aphezulu e-acetylcholine. Ngenxa yokuba i-Centrophenoxine iphucula imisebenzi eyahlukeneyo ye-cholinergic, enye yezinto eziveliswayo yi-choline, phakathi kwezinye iifospholipids ezahlukeneyo.

Ukuphuculwa kwemisebenzi yokuqonda

ICentrophenoxine inokusetyenziswa njengesiyobisi se-DMAE kwaye oku kubaluleke kakhulu, njengoko le molekyuli isebenza kakuhle ekunciphiseni ukwakhiwa kwemolekyuli ngaphakathi kwengqondo enokubangela ukunciphisa kakhulu kwimisebenzi yokuqonda. Ngezi molekyuli zisusiweyo, abantu abadala banokucothisa ukwaluphala kwabo kwaye babuye umva kwezinye iziphumo ebezindala zokwaluphala.

ICentrophenoxine inezixhobo zokulwa ukuguga kunye Neuroprotential

ICentrophenoxine iye yaboniswa ukwandisa ixesha lokuphila kwamagundane ukuya kuthi ga kwiipesenti ezingama-50.

ICentrophenoxine iphucula uMood kunye noKhuthazo, inokunceda ukunciphisa uxinzelelo.

Izifundo zezilwanyana zicebisa ukuba i-centrophenoxine ineziphumo zokulinganisa ezinokuxhalabisa.ur

I-Meclofenoxate (Centrophenoxine) imetabolism

I-Centrophenoxine isebenza ikakhulu ngokuhambisa kunye nokuphucula iintshukumo ze-choline. I-Choline ngumanduleli we-acetylcholine, i-neurotransmitter eyimfuneko kwaye engenamda edibene ngokuqinileyo ne-cuitive acuity, plasticity, kunye nememori. Akucaci ukuba ngqo kangakanani istrophenoxine ilonyusa amanqanaba e-choline kunye ne-acetylcholine, kodwa kucingelwa ukuba iyaphula ngokwemvelo iye kwi-choline okanye iguqukele kwi-phospholipid ephakathi esetyenziselwa ukuvelisa i-acetylcholine. Nokuba yeyiphi na indlela, yindawo ye-cholinergic eyenza i-centrophenoxine enamandla e-nootropic ye-potentiator ngamandla ayo.

Ukongeza ekunyuseni kwemveliso ye-acetylcholine, isetyrophenoxine ikwabizwa ngokuba sisinamandla se-neuro esivuselela imisebenzi yobuchopho ngokubanzi ngokuphucula ukufakwa kweglucose kunye nokwandisa ukuthathwa kweoksijini. Ngokwenza njalo, i-centrophenoxine yenza ukuba ingqondo isebenze kakuhle, ngaloo ndlela iphucula ukugxila, ukugxininisa, kunye nokucaca kweengcinga, ukususa into ebizwa ngokuba yinkungu yobuchopho. Njenge-antioxidant enamandla, ikhusela iiradicals simahla, ikhuphe iityhefu kwaye ithathe inxaxheba kulungiso lweeseli ezonakeleyo. Okokugqibela, iyawubuyisa ukuguga kwengqondo ngokunciphisa okanye ukuphelisa ukwakhiwa kweemveliso zenkunkuma ye-metabolic ethathwa ngokuba "ayinanto yakwenza nokugqobhoza imibala."

I-Meclofenoxate (Centrophenoxine) iziphumo kunye nokukhuseleka.

I-Centrophenoxine ngokubanzi ithathwa njengekhuselekileyo kwaye ingelona ityhefu. Isetyenziswe iminyaka emalunga nama-50 ngaphandle kokuba kuqatshelwe.

Kuthiwa sisiyobisi esinyamezelayo kubantu abadala abaninzi abasempilweni kunye nes senile ebangwa kukulahleka kwememori.

Nangona kunjalo, abanye abasebenzisi baye bahlangabezana neziphumo ezibi ezinobuncinci kunye nezincinci, kubandakanya isicaphucaphu, intloko ebuhlungu, imiba yesisu, kunye nokungalali.‍

ICentrophenoxine ayicetyiswa kubafazi abakhulelweyo ngenxa yomxholo we-DMAE.

I-Meclofenoxate (Centrophenoxine) umthamo wepowder

ICentrophenoxine ifumaneka ngaphezulu kwekhawuntari kwiicaphulethi eziqukethe i-200 ukuya kwi-300 mg nganye. Uvavanyo lweklinikhi oluvavanye iziphumo ze-centrophenoxine kwimisebenzi yengqondo isebenzise idosi yemihla ngemihla ye

I-1,200 mg kubantu abadala asempilweni kunye nethamo ukuya kuthi ga ku-2,000, XNUMX mg kwizigulo zengqondo.

Ukufakwa

ICentrophenoxine ngumthombo olungileyo we-choline, ungayifumana kwizitokhwe ezininzi ze-nootropic - ezinye zezona zixhaphakileyo yiNoopept kunye neRacetams.

I-Centrophenoxine kunye ne-Aniracetam Stack

Nanku umzekelo we-stroprophenoxine isitaki esibandakanya i-aniracetam eyaziwayo ye-racetam yokunyusa ukugcinwa kwememori, imvakalelo, ubuchule bokuqamba, ngelixa kunciphisa uxinzelelo.

1-2x ngosuku

I-250 mg Centrophenoxine

I-750 mg Aniracetam

ICentrophenoxine kunye neNoopept Stack

Nanku umzekelo we-stroprophenoxine isitaki esineNoopept, esi sitaki sinokuphucula inkumbulo kunye nokufunda, ngelixa zibonelela ngeepropathi ze-neuroprotective.

1-2x ngosuku

I-250 mg Centrophenoxine

I-20 mg yeNoopept

isingqiniso:

  • Kwindima ye-intracellular physicochemistry ekubonakaliseni ubungakanani besini ngexesha lokuguga kunye nesiphumo se -roprophenoxine. Uphengululo. I-Zs-Nagy I et al. UArch Gerontol Geriatr. (1989)
  • Unyango lweCholinergic lwe-antipsychotic-indied tardive dyskinesia. Tammenmaa-Aho I, Asher R, Soares-Weiser K, Bergman H. Cochrane Database Syst Rev 2018 Matshi 19
  • Umsebenzi weCytotoxic weearhente ze-alkylating phambi kwe-centrophenoxine kunye neemveliso zayo ze-hydrolysis. Sladek NE. J Theracol Exp Ther. Ngo-1977 ngoDisemba
  • Amandla okusebenza komsebenzi we-antitumor we-cyclophosphamide ngu-centrophenoxine. Kanzawa F, Hoshi A, Tsuda S, Kuretani K. Gan. Ngo-1972 Aug
  • I-Centrophenoxine: iimpembelelo kwingqondo yokwaluphala ye-mammalian. Nandy K et al. UJ Am Geriatr Soc. (1978)
  • Iziphumo ezahlukileyo ze-meclofenoxate ekulahlekelweni kwememori kubantu abadala. UMarcer D et al. Ukwaluphala. (1977)

ISIQINISEKISO NESIBONELELO:

Le nto ithengiselwe uKwenziwa koPhando kuphela. Imigaqo yokuthengisa Faka isicelo. Ayisetyenziselwa uBuntu, okanye oNyango, iZilwanyana, okanye abaNtu.