I-Urolithin i-8-Methyl Ether

Aprili 8, 2021

I-Urolithins ziyimetabolism yesibini ye-ellagic acid ethathwe kwi-ellagitannins. Ebantwini i-ellagitannins iguqulwa yi-gut microflora ibe yi-ellagic acid eguqulwa i-urolithins A, urolithin B, urolithin C kunye ne-urolithin D kumathumbu amakhulu.

I-Urolithin A 8-Methyl Ether (35233-17-1) ividiyo

 

I-Urolithin A eyi-8-Methyl Ether 35233 17-1-XNUMX)iinkcukacha

Igama lemveliso I-Urolithin I-8-Methyl Ether powder
Igama leKhemikhali 3-hydroxy-8-methoxy-6H-benzo [c] chromen-6-inye;

3-hydroxy-8-methoxybenzo [c] chromen-6-inye;

35233-17-1;

Ikhonkco

I-SMR000386929;

IChemDiv3_002724;

I-Urolithin A eyi-8-Methyl Ether;

Inani leCAS 35233-17-1
InChIKey IGJLBTGXYKPECW-UHFFFAOYSA-N
I molecular Fi-ormula C14H10O4
I molecular WSibhozo 242.23
IMasaisotopic Mass 242.057909 g / mol
Indawo yokunyibilika 242 ° C (Solv: acetic acid (64-19-7))
Indawo yokubilisa  479.9 ± 38.0 ° C (Kuxelwe kwangaphambili)
Dikhosi 1.375 0.06 3 g / cmXNUMX (Kuxelwe kwangaphambili)
I-Biological Half-Life N / A
umbala Ukukhanya okuqaqambileyo okumnyama kakhulu kuQinisekile
Sukufaneleka  I-Acetone (Kancinci, Sonicated) DMSO (Kancinci, Sonicated), Methanol (Kancinci)
Sisibetho Tukushisa  I-Hygroscopic, -20 ° C I-Freezer, Ngaphakathi kwemoya engenayo
Aukuguquka I-Urolithin A-8-Methyl Ether iphakathi ekudibaneni kwe-Urolithin A (U847000), eyona metabolite iphambili ye-Ellagitannin kwaye ibonisa iipropathi ezichasene nokudumba kunye ne-antioxidant.

 

isingqiniso

[1] UEspín, uJuan Carlos; Larrosa, Mar; UGarcía-Conesa, uMaría Teresa; UTomás-Barberán, uFrancisco (2013). "Ukubaluleka kwebhayiloji ye-Urolithins, iGut Microbial Ellagic Acid-Derives Metabolites: Ubungqina ukuza kuthi ga ngoku". Ubungqina obusekwe kubungqina obuncedisayo kunye nenye iyeza. 2013: 270418. ikhonkco: 1155/2013/270418. ISSN1741-427X. PMC 3679724. PMID 23781257.

[2] Ryu, Dongryeol; UMouchiroud, uLaurent; UAndreux, uPénélope A; UKatsyuba, uElena; UMoullan, uNorman; UNicolet-dit-Félix, uAmandine A; UWilliam, uEvan G; Jha, Pooja; ISasso, iGiuseppe Lo (2016). "I-Urolithin A inducus mitophagy kwaye yongeza ixesha lokuphila kwi-C. elegans kwaye yonyusa ukusebenza kwemisipha kwiintonga". Amayeza endalo. 22 (8): 879-888. ikhonkco: 1038 / nm. 4132. IINKCUKACHA:

[3] Ishimoto, Hidekazu; Shibata, Mari; UMyojin, uYuki; Ito, Hideyuki; USosimoto, uYukio; Tai, Akihiro; Hatano, Tsutomu (2011). "Kwi-vivo anti-inflammatory kunye ne-antioxidant iipropathi ze-ellagitannin metabolite urolithin A" (PDF). Iileta zeBioorganic kunye nezeMedical Chemistry. 21 (19): 5901-5904. ikhonkco: 1016 / j.bmcl.2011.07.086. IINKCUKACHA:

[4] IKasimsetty, SG, okqhubekayo: J. Agri. Ukutya. I-Chem., 58, 2180 (2010);

[5] IBialonska, D., okqhubekayo: J. Agri. Ukutya. I-Chem., 57, 10181 (2009);